Neurosurgical Focus March 2015

The effects of alternating electric fields in glioblastoma: current evidence on therapeutic mechanisms and clinical outcomes.
Introduction: Neurooncology: update on therapeutic options.
Molecular features assisting in diagnosis, surgery, and treatment decision making in low-grade gliomas.
An evidence-based treatment algorithm for the management of WHO Grade II and III meningiomas.
A practical review of prognostic correlations of molecular biomarkers in glioblastoma.
Ipilimumab and craniotomy in patients with melanoma and brain metastases: a case series.
Stereotactic radiosurgery and immunotherapy for metastatic spinal melanoma.
Preoperative endovascular embolization of meningiomas: update on therapeutic options.
Effects of convection-enhanced delivery of bevacizumab on survival of glioma-bearing animals.
Therapeutic strategies to improve drug delivery across the blood-brain barrier.
Renaissance of laser interstitial thermal ablation.
Quinoline-based antimalarial drugs: a novel class of autophagy inhibitors.
Aggressive repeat surgery for focally recurrent primary glioblastoma: outcomes and theoretical framework.
Novel delivery methods bypassing the blood-brain and blood-tumor barriers.

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