New Book: Ischemic Stroke

Ischemic Stroke (Emergency Management in Neurology)

By Giuseppe D’Aliberti, Marco Longoni, Cristina Motto, Valentina Oppo, Valentina Perini, Luca Valvassori, Simone Vidale

Ischemic Stroke (Emergency Management in Neurology)
List Price: $39.99

Editorial Reviews

From the Back Cover
This book provides detailed practical guidance on the management of acute ischemic stroke in the clinical settings encountered in daily practice. Real-life cases are used to depict a wide range of clinical scenarios and to highlight significant aspects of management of ischemic stroke. In addition, diagnostic and therapeutic protocols are presented and helpful decision-making algorithms are provided that are specific to the different professionals involved in delivery of acute stroke care and to differing types of hospital facility. The coverage is completed by the inclusion of up-to-date scientific background information relevant to diagnosis and therapy. Throughout, the approach adopted is both practical and multidisciplinary. The book will be of value for all practitioners involved in the provision of acute stroke care, and also for medical students.
About the Author
Giuseppe Antonio D’Aliberti received his MD from Catania University School of Medicine in Italy in 1983 and then trained in Neurosurgery in Italy and overseas. He was appointed as a neurosurgeon in the Neurosurgical Department of Niguarda Ca’ Granda Hospital, Milan, in 1987. He served as Vice-Director of the department from 2003 to 2009 and as Chairman from 2009 to 2011. He also served as tutor in Neurosurgery at the Neurosurgical Training School of the University of Milan from 2001 to 2011. He has performed more than 3000 major surgical procedures, mostly for benign cerebral tumours, aneurysms, cerebral AVMs, and spinal tumours/AVMs. He has published 230 refereed articles and been invited to deliver lectures at over 100 national and international conferences.
Marco Longoni completed his medical studies at the University of Milano-Bicocca, Italy, in 2001 and then undertook a residency and fellowship in Neurology at the university. He has also since completed a fellowship in Radiology. He currently works at the Niguarda Ca’ Granda Hospital in Milan, having previously been a neurologist in the Neuroscience Department of Lecco Hospital, Italy (2007–14).Valentina Oppo gained her MD from the University of Cagliari, Italy in 2009 and subsequently undertook residencies at the University of Cagliari and the University of Milano-Bicocca. She completed her specialization in Neurology at the University of Milano-Bicocca in 2015 and is currently a Fellow in the Neurology Department at Niguarda Ca’ Granda Hospital, Milan.
Valentina Perini completed her degree in Medicine and Surgery at the University of Palermo, Italy, in 2008. She entered the Neurology residency program at the university in 2011 and since April 2015 has been undertaking a traineeship in the Stroke Unit at Niguarda Ca’ Granda Hospital in Milan.
Luca Piero Valvassori Bolgè obtained his degree in Medicine and Surgery (cum laude) from the University of Milan in 1985 and completed his specialization in Radiology and Radiotherapy at the University of Milan in 1989. He has been a staff neuroradiologist at Niguarda Ca’ Granda Hospital in Milan since December 1989 and Vice-Director of the Department of Neuroradiology since 2009.
Simone Vidale graduated in Medicine and then specialized in Neurology at the University of Insubria, Varese, Italy. He currently works in the Department of Neurology, Sant’Anna Hospital, Como, Italy, focusing on strokes, neurological emergencies, and Alzheimer’s disease and other dementias. He served as National Secretary of the Italian Association Against Stroke from 2007 to 2009 and was co-author of chapters on risk factors and primary prevention in the Italian Stroke Guidelines.

A review invalidates thousands of studies of the brain

A computer failure and bad widespread practices call into question 15 years of research

Functional MRI (fMRI) is 25 years old, yet surprisingly its most common statistical methods have not been validated using real data. Eklund et al. , used resting-state fMRI data from 499 healthy controls to conduct 3 million task group analyses. Using this null data with different experimental designs, they estimate the incidence of significant results. In theory, they should find 5% false positives (for a significance threshold of 5%), but instead they found that the most common software packages for fMRI analysis (SPM, FSL, AFNI) can result in false-positive rates of up to 70%. These results question the validity of some 40,000 fMRI studies and may have a large impact on the interpretation of neuroimaging results.


The most widely used task functional magnetic resonance imaging (fMRI) analyses use parametric statistical methods that depend on a variety of assumptions. In this work, we use real resting-state data and a total of 3 million random task group analyses to compute empirical familywise error rates for the fMRI software packages SPM, FSL, and AFNI, as well as a nonparametric permutation method. For a nominal familywise error rate of 5%, the parametric statistical methods are shown to be conservative for voxelwise inference and invalid for clusterwise inference. Our results suggest that the principal cause of the invalid cluster inferences is spatial autocorrelation functions that do not follow the assumed Gaussian shape. By comparison, the nonparametric permutation test is found to produce nominal results for voxelwise as well as clusterwise inference. These findings speak to the need of validating the statistical methods being used in the field of neuroimaging.

New Book: Image-Guided Stereotactic Radiosurgery

Image-Guided Stereotactic Radiosurgery: High-Precision, Non-invasive Treatment of Solid Tumors
By Harun Badakhshi

Image-Guided Stereotactic Radiosurgery: High-Precision, Non-invasive Treatment of Solid Tumors

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This book provides the reader with a detailed update on the use of stereotactic radiosurgery (SRS) in patients with lesions of the brain and other parts of the body. The aim is not simply to explain the application of SRS and document its value with reference to the author’s own clinical experiences and other published evidence, but also to contextualize the technology within a new strategic concept of cancer care. When embedded within an appropriate conceptual framework, technology becomes pivotal in changing therapeutic strategies. A new paradigm that is increasingly impacting on clinical practice is the oligometastatic state, on the basis that long-term survival might be achieved in patients with a low volume and number of metastatic lesions. This book accordingly addresses the value of SRS in patients with oligometastases of solid tumors to the brain, lung, spine, and liver. In addition, it examines the use of SRS in patients with diverse brain lesions, early-stage stage lung cancer, liver cancer, and early-stage prostate cancer. Readers will be persuaded that SRS, using cutting-edge imaging technologies to deliver precisely targeted radiation therapy, represents an exciting non-invasive procedure that holds great promise for the present and the future of cancer care.


Dr Harun Badakhshi is Chief Physician and chairman of clinical radiation oncology at Ernst von Bergmann Medical Center, an academic teaching hospital of Humboldt University Berlin. He also serves as senior lecturer / assoc. professor at Charité School of Medicine Humboldt University Berlin, and is holding various functions in regional and European organizations and societies that are related to cancer research and education. He has previously worked as vice chairman of radiation oncology at University Hospital Charité.
His research interest is primarily in neurooncology, lung and breast cancer, and metastases research. A focus of his research lies, especially, in studying effects of image-guided high precision radiotherapy for benign and malignant tumors, as well in investigations about curative potentials for cancer with oligometastases.
He has published about 50 original peer-reviewed research papers to date and many reviews on different aspects of medicine, including prevention, education, health economics. He serves as a reviewer for more than 10 specialized journals, and as an appraiser for regional medical organizations and physician chamber.

Product Details

  • Published on: 2016-07-27
  • Original language: English
  • Number of items: 1
  • Dimensions: .0″ h x .0″ w x .0″ l, .0 pounds
  • Binding: Hardcover
  • 271 pages

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