Intracranial intravascular papillary endothelial hyperplasia (IPEH), also referred to as Masson’s tumor, is a condition that rarely occurs in the nervous system. IPEH most frequently occurs extracranially in the skin of the face, skull, neck, and trunk and can easily be mistaken clinically, radiologically, and histologically for angiosarcoma, organizing hematoma, or other vascular malformations. IPEH accounts for roughly 2% of all vascular tumors and is extremely rare intracranially, with only 23 reported cases compared with more than 300 cases of IPEH occurring in the skin and subcutaneous tissue.

Charalambouset al. reported the case of a patient with an IPEH in the pineal region who underwent complex resection and experienced reversal of neurological symptoms ¹⁾.

There has been only one previous report of intravascular papillary endothelial hyperplasia occurrence in the pineal region. Retzlaff et al. from Milwaukee reported a second case and a review of the literature ²⁾.