Pediatric traumatic brain injury guidelines

Pediatric traumatic brain injury guidelines

see Guidelines for the Management of Pediatric Severe Traumatic Brain Injury, Third Edition

In a systematic review and guideline appraisal for pediatric clinical practice guidelines (CPGs) concerning the acute management of Pediatric Traumatic Brain Injury. Targeted guideline creation specific to the pediatric population has the potential to improve the quality of acute TBI clinical practice guidelines (CPGs).

Furthermore, it is crucial to address the applicability of a guideline to translate the CPG from a published manuscript into clinically relevant local practice tools and for resource limited practice settings 1).

Guidelines for Diagnosing and Managing Pediatric Concussion

Guidelines.


Thromboprophylaxis in Traumatic brain injury:

Low-molecular-weight heparin (LMWH) prophylaxis in pediatric traumatic brain injury appears to be more effective than unfractionated heparin (UH) in preventing venous thromboembolism (VTE). Large, multicenter prospective studies are warranted to confirm the superiority of LMWH over UH in pediatric patients with traumatic brain injury. Moreover, outcomes of VTE prophylaxis in the very young remain understudied; therefore, dedicated studies to evaluate this population are needed 2).


1)

Appenteng R, Nelp T, Abdelgadir J, Weledji N, Haglund M, Smith E, Obiga O, Sakita FM, Miguel EA, Vissoci CM, Rice H, Vissoci JRN, Staton C. A systematic review and quality analysis of pediatric traumatic brain injury clinical practice guidelines. PLoS One. 2018 Aug 2;13(8):e0201550. doi: 10.1371/journal.pone.0201550. eCollection 2018. PubMed PMID: 30071052; PubMed Central PMCID: PMC6072093.
2)

van Erp IA, Gaitanidis A, El Moheb M, Kaafarani HMA, Saillant N, Duhaime AC, Mendoza AE. Low-molecular-weight heparin versus unfractionated heparin in pediatric traumatic brain injury. J Neurosurg Pediatr. 2021 Feb 12:1-6. doi: 10.3171/2020.9.PEDS20615. Epub ahead of print. PMID: 33578391.

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