Test your knowledge about BCL2L13 and its potential role in glioblastoma

Certainly, here's a quiz to test your knowledge about BCL2L13 and its potential role in glioblastoma:

What is BCL2L13's role within the BCL-2 protein family?
a) Promotion of apoptosis
b) Inhibition of apoptosis
c) Regulation of cell division
d) Promotion of cell growth

What does BCL2L13 stand for?
a) B-cell leukemia/lymphoma 2-like protein 13
b) Bcl-rambo
c) Bcl2-L-13
d) All of the above

In the context of glioblastoma, what is the primary function of BCL2L13?
a) Promotion of tumor growth
b) Inhibition of mitophagy
c) Regulation of apoptosis
d) Promotion of mitochondrial fission and mitophagy

How does BCL2L13 potentially impact glioblastoma cell behavior?
a) By inhibiting cell invasion
b) By promoting programmed cell death
c) By enhancing cell proliferation and invasion
d) By regulating DNA repair mechanisms

In a study by Wang et al., what was the main finding regarding BCL2L13 in glioblastoma?
a) BCL2L13 is downregulated in GBM.
b) BCL2L13 has no significant impact on GBM cells.
c) BCL2L13 is upregulated in GBM and promotes mitophagy through DNM1L-mediated mitochondrial fission.
d) BCL2L13 is unrelated to GBM progression.

What is DNM1L's role in the context of BCL2L13 and glioblastoma?
a) It inhibits BCL2L13 expression.
b) It promotes apoptosis.
c) It mediates mitochondrial fission and mitophagy.
d) It has no connection to glioblastoma.

Why is understanding the role of BCL2L13 in glioblastoma important?
a) Because it is a well-established target for glioblastoma treatment.
b) Because it plays a role in DNA repair.
c) Because it can potentially be a molecular target for therapy.
d) Because it is a commonly mutated gene in glioblastoma.


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