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Medulloblastoma classification MBMethPred: a computational framework for the accurate classification of childhood medulloblastoma subgroups using data integration and AI-based approaches High frequency of WNT-activated medulloblastomas with <em>CTNNB1</em> wild type suggests a higher proportion of hereditary cases in a Latin-Iberian population Subtyping of Group 3/4 medulloblastoma as a potential prognostic biomarker among patients treated with reduced … Read more

Glioblastoma prognostic markers Latest PubMed Glioblastoma prognostic markers related articles Different states of stemness of glioblastoma stem cells sustain glioblastoma subtypes indicating novel clinical biomarkers and high-efficacy customized therapies Preoperative Immune-Inflammatory Status of the Patients With Newly-Diagnosed Glioblastoma – Could It Genuinely Predict Their Survival? Intratumoral thrombosis as a histological biomarker for predicting epidermal growth … Read more

DNA methylation in intracranial aneurysm pathogenesis Latest DNA methylation in intracranial aneurysm pathogenesis PubMed related Articles DNA methylation regulator-mediated modification patterns and risk of intracranial aneurysm: a multi-omics and epigenome-wide association study integrating machine learning, Mendelian randomization, eQTL and mQTL data DNA methylation of the MAP3K10 gene may participate in the development of intracranial aneurysm … Read more

Lenticulostriate artery aneurysm Microsurgical excision of a ruptured distal lenticulostriate aneurysm in a child A case of middle cerebral artery large circumferential aneurysm treated with bypass-assisted trapping surgery High-Flow Bypass and Clip Trapping of a Giant Fusiform Middle Cerebral Artery (M1) Aneurysm: Technical Case Instruction Middle Cerebral Artery and Lenticulostriate Artery Revascularization for Clipping of … Read more

Thiopental Thiopental (Pentothal®) Thiopental in neurosurgery Thiopental and decompressive craniectomy as last-tier ICP-treatments in aneurysmal subarachnoid hemorrhage: is functional recovery within reach? Decompressive craniectomy as a second/third-tier intervention in traumatic brain injury: A multicenter observational study Antithrombotic agent usage before ictus in aneurysmal subarachnoid hemorrhage: relation to hemorrhage severity, clinical course, and outcome First Case … Read more

Antibiotics for spondylodiscitis treatment Conservative versus early surgical treatment in the management of pyogenic spondylodiscitis: a systematic review and meta-analysis Massive empyema due to <em>Lactococcus garvieae</em> Pharmacokinetic and pharmacodynamic considerations for optimizing antimicrobial therapy used to treat bone and joint infections: an evidence-based algorithmic approach Surgical treatment of <em>Candida albicans</em> spondylodiscitis Carbapenem-Resistant <em>Pseudomonas aeruginosa</em> Spondylodiscitis … Read more

Magnetic resonance image-guided laser interstitial thermal therapy for glioblastoma Persistent Peri-Ablation Blood-Brain Barrier Opening After Laser Interstitial Thermal Therapy for Brain Tumors Biopsy and Ablation of H3K27 Glioma Using Skull-Mounted Smartframe Device: Technical Case Report Cerebral edema induced by laser interstitial thermal therapy and radiotherapy in close succession in patients with brain tumor see Glioblastoma treatment. … Read more

Propofol Propofol is a potent intravenous (IV) anesthetic agent used for the induction and maintenance of general anesthesia during surgical procedures and medical interventions. It is one of the most widely used and recognized anesthesia drugs in clinical practice. Here are some key points about propofol: Induction of Anesthesia: Propofol is often used to rapidly … Read more

Woven EndoBridge (WEB) Clipping of a Rebleeding Ruptured Aneurysm After Woven EndoBridge Treatment The Woven EndoBridge device, an effective and safe alternative endovascular treatment of intracranial aneurysm-systematic review Clipping of an Unruptured Middle Cerebral Artery Aneurysm Recurrence Previously Treated With Woven EndoBridge: 2-Dimensional Operative Video A novel intrasaccular aneurysm device with high complete occlusion rate: … Read more

Aneurysm clipping Latest PubMed Aneurysm clipping-related articles The Effect of Preoperative Three Dimensional Modeling and Simulation on Outcome of Intracranial Aneursym Surgery Rathke’s cleft cyst discovered with ruptured anterior communicating artery aneurysm: a case report Is there any risk for recurrence of a completely clipped intracranial aneurysm? The Cost of Operating: Analysis of Single-Use Instrument … Read more

Cerebrospinal fluid fistula after endoscopic skull base surgery prevention Latest PubMed Articles of Cerebrospinal fluid fistula after endoscopic skull base surgery prevention Does lumbar drainage reduce postoperative cerebrospinal fluid leak after endoscopic endonasal skull base surgery? A prospective, randomized controlled trial Avoiding complications in endoscopic skull base surgery CLOSURE OF NASOCRANIAL FISTULAS WITH “BATH-PLUG” TECHNIQUE AND MULTILAYER RECONSTRUCTION Double flap technique for reconstruction of anterior skull base defects after craniofacial tumor resection: technical note Vascularised local and free flaps in … Read more

What type of FCD is considered the best candidate for curative surgery, even if it involves lesions in brain eloquent areas? a) Type I FCD b) Type IIa FCD c) Type IIb FCD d) Type III FCD What is the most common surgical procedure for FCD that aims to eliminate the source of seizures while … Read more

What is the significance of foramen magnum stenosis in achondroplasia? a) It is a cosmetic issue with no medical consequences. b) It can lead to compression of the brainstem and spinal cord, resulting in severe health problems. c) It only affects adults with achondroplasia. d) It is completely unrelated to achondroplasia. What contributes to the … Read more

What was the median age of patients analyzed in the systematic review of awake surgery for glioma resection during pregnancy? a) 25 years b) 30.5 years c) 35 years d) 40 years In the same review, what percentage of patients underwent awake surgery in the third trimester of pregnancy? a) 25% b) 50% c) 67% … Read more

What is the primary status of DBS as a treatment for Alcohol Use Disorder (AUD)? a) It is a standard and FDA-approved treatment for AUD. b) It is experimental and emerging, with ongoing research and clinical trials. c) It is widely available and accessible. d) It is a widely used alternative to medications. Which brain … Read more

Certainly, here’s a quiz to test your knowledge about BCL2L13 and its potential role in glioblastoma: What is BCL2L13’s role within the BCL-2 protein family? a) Promotion of apoptosis b) Inhibition of apoptosis c) Regulation of cell division d) Promotion of cell growth What does BCL2L13 stand for? a) B-cell leukemia/lymphoma 2-like protein 13 b) … Read more

What is the primary purpose of external lumbar CSF drainage in the context of cerebral vasospasm prevention? a) To directly remove blood from the brain’s blood vessels. b) To increase intracranial pressure. c) To monitor CSF characteristics. d) To administer calcium channel blockers. Why is lowering intracranial pressure through CSF drainage beneficial in preventing cerebral … Read more

Intracranial Aneurysm treatment Embolization of unruptured wide-necked aneurysms at the MCA bifurcation using the Neuroform atlas stent-assisted coiling: a two-center retrospective study Microsurgical clipping and endovascular intervention for middle cerebral artery aneurysm: A meta-analysis Endovascular embolization with EVOH for the treatment of a Rasmussen aneurysm Concomitant valve surgery is associated with worse outcomes in surgical … Read more

Magnetic resonance imaging for idiopathic intracranial hypertension diagnosis MRI features of idiopathic intracranial hypertension are not prognostic of visual and headache outcome VENOUS OVERLOAD CHOROIDOPATHY ASSOCIATED WITH IDIOPATHIC INTRACRANIAL HYPERTENSION How to understand an enlarged Meckel’s cave? An anatomical study Atrium meningioma: Transtubular posterior intraparietal sulcus approach Pediatric optic nerve and globe measurements on magnetic … Read more

Glioblastoma survival Life expectancy in glioblastoma patients who had undergone stereotactic biopsy: a retrospective single-center study THOC2 expression and its impact on 5-fluorouracil resistance in glioblastoma multiforme Immuno-PET Imaging of CD69 Visualizes T-Cell Activation and Predicts Survival Following Immunotherapy in Murine Glioblastoma SRSF1 induces glioma progression and has a potential diagnostic application in grading primary … Read more

S100B in traumatic brain injury S100B protein as a biomarker and predictor in traumatic brain injury Prognostic value of serum biomarkers in patients with moderate-severe traumatic brain injury, differentiated by Marshall CT classification Post-mortem detection of neuronal and astroglial biochemical markers in serum and urine for diagnostics of traumatic brain injury Association between Cerebrospinal Fluid … Read more

DECSA trial Chronic subdural hematoma (CSDH) is a common neurological disease with a rapidly rising incidence due to increasing age and widespread use of anticoagulants. Surgical intervention by burr hole craniotomy (BHC) is the current standard practice for symptomatic patients, but associated with complications, a chronic subdural hematoma recurrence rate of up to 30% and increased mortality. Dexamethasone (DXM) therapy is, therefore, used as … Read more

Adult spinal deformity surgery outcome Latest PubMed Adult spinal deformity surgery outcome Articles Adherence to the Obeid coronal malalignment classification and a residual malalignment below 20 mm can improve surgical outcomes in adult spine deformity surgery Anterior To Psoas lumbar and lumbosacral combined with posterior reconstruction in Adult Spinal Deformity: A bicentric European study Demineralized cortical … Read more

Nigeria Nigeria is the most populous country in Africa with an estimated 206 million inhabitants served by less than 300 neurologists and 131 neurosurgeons. Neurological conditions account for approximately 18% of all medical emergencies. Neurocritical care challenges in Nigeria are as complex as they are in other low-to-middle-income countries (LMICs). These include a high burden of neurological diseases, poor pre-hospital care, delays in transfer, lack … Read more

Traumatic brain injury treatment Acute activation of innate immune response in the brain, or neuroinflammation, protects this vital organ from a range of external pathogens and promotes healing after traumatic brain injury. Secondary brain injury treatment see Secondary brain injury treatment Transfer Traumatic brain injury transfer. Management in Emergency Room Blood pressure and oxygenation Level II: monitor BP and … Read more

Craniopharyngioma endoscopic endonasal approach Latest Craniopharyngioma endoscopic endonasal approach PubMed-related Articles Current Role of Endoscopic Endonasal Approach for Craniopharyngiomas: A 10-Year Systematic Review and Meta-Analysis Comparison with the Open Transcranial Approach Endoscopic Endonasal Transtuberculum Approach for Pediatric Tuberoinfundibular Craniopharyngioma: 2-Dimensional Operative Video Endoscopic Endonasal Approach in Craniopharyngiomas: Representative Cases and Technical Nuances for the Young … Read more

Pituitary apoplexy Diagnosis and management of pituitary apoplexy: a Tunisian data Takotsubo syndrome and its linkage to neuroendocrinological disorders: a case report Natural history of non-functioning pituitary microadenomas – results from the UK NFPA consortium Pituitary Apoplexy Following Elective Total Hip Replacement Pituitary Apoplexy in Pregnancy: What do We Know? Euvolaemic hyponatraemia as a rare … Read more

Split cord malformation Oxidative balance scores and neural crest cell-related congenital anomalies Folic acid – importance for human health and its role in COVID-19 therapy A clinical clue toward recognition of split cord malformation type-I resembling meningocele in neonates Case report: Sacral agenesis in two boxer dogs: clinical presentation, diagnostic investigations, and outcome Are there … Read more

Vorasidenib Vorasidenib in IDH1- or IDH2-Mutant Low-Grade Glioma Targeted Options for Glioma Looking Good Vorasidenib and ivosidenib in IDH1-mutant low-grade glioma: a randomized, perioperative phase 1 trial Imidazole and Biphenyl Derivatives as Anti-cancer Agents for Glioma Therapeutics: Computational Drug Repurposing Strategy Pharmacophore-based Identification of Potential Mutant Isocitrate Dehydrogenases I/2 Inhibitors: An Explorative Avenue in Cancer … Read more

Glioma biomarker 1p/19q co-deletion. ATRX. BRAF. CDKN2A. Chromosome 7 Gain and Chromosome 10 Loss EGFR H3F3A. H3K27M IDH1 and IDH2. MAPK Pathway MGMT MN1 MYB. TERT. TP53. see Glioblastoma biomarker. Diffuse gliomas exhibits different molecular and genetic profiles with a wide range of heterogeneity and prognosis. Recently, molecular parameters including ATRX gene mutation, P53, and IDH mutation status or absence or presence of 1p/19q co-deletion have become a crucial … Read more

Mild traumatic brain injury Latest mild traumatic brain injury- related PubMed Articles Long-term follow-up of critically ill traumatic brain injury patients: from intensive care parameters to patient and caregiver-reported outcome The 8 January 2020 theatre ballistic missile attack on US soldiers stationed at Al Asad Air Base, Iraq: case series using a concussion subtypes framework … Read more

Craniopharyngioma (CP) Endoscopic Endonasal Approach in Craniopharyngiomas: Representative Cases and Technical Nuances for the Young Neurosurgeon Obesity Risk of Pediatric Central Nervous System Tumor Survivors: A Cross-Sectional Study Evaluating eating behaviour, energy homeostasis and obesity in childhood onset craniopharyngioma: A feasibility study Safety of growth hormone replacement therapy in childhood-onset craniopharyngioma: a systematic review and … Read more

Alzheimer’s disease differential diagnosis with normal pressure hydrocephalus Latest PubMED Related Articles Brain linear measurements for differentiating Normal Pressure Hydrocephalus from Alzheimer’s disease: an exploratory study Cerebrospinal Fluid Biomarkers in iNPH: A Narrative Review Brain ventricles, CSF and cognition: a narrative review A Comparison of Cerebrospinal Fluid Beta-Amyloid and Tau in Idiopathic Normal Pressure Hydrocephalus … Read more

Glioblastoma immunotherapy Novel Immunotherapeutic Approaches for the Treatment of Glioblastoma Applications of organoid technology to brain tumors Anti-tumor efficacy of anti-GD2 CAR NK-92 cells in diffuse intrinsic pontine gliomas The SNP rs755622 is associated with immune activation in glioblastoma Tumor Microenvironment and Glioblastoma Cell Interplay as Promoters of Therapeutic Resistance Integrating machine learning and bioinformatics … Read more

Decompressive craniectomy for intracranial hypertension treatment Delayed recovery from severe refractory intracranial hypertension due to expansion of skin and pericranium stretch after decompressive craniectomy Bacterial Brain Abscess and Life-Threatening Intracranial Hypertension Requiring Emergent Decompressive Craniectomy After SARS-CoV-2 Infection in a Healthy Adolescent Current status and outlook for the management of intracranial hypertension after traumatic brain … Read more

Peptic ulcer disease A Reappraisal of the Pathophysiology of Cushing Ulcer: A Narrative Review Randomised clinical trial: 3-year interim analysis results of the VISION trial to evaluate the long-term safety of vonoprazan as maintenance treatment in patients with erosive oesophagitis Laparoscopic versus laparoscopy-assisted suturing of perforated peptic ulcers (meta-analysis) Comparison of Concordance of Peptic Ulcer … Read more

Carotid artery stenting (CAS) Latest Pubmed Carotid artery stenting Related Articles Stenting of the Common Carotid Artery Ostium: Balloon Catheter Lifting-Up Technique With a Gooseneck Snare Young Patients Undergoing Carotid Stenting Procedures Have an Increased Rate of Procedural Failure at One Year Follow-Up Corroded iron stent increases fibrin deposition and promotes endothelialization after stenting Commentary: … Read more

Intracranial hemorrhage from Dengue Expanded Dengue Syndrome Presenting as Intracranial Hemorrhage, Fever, and Rhabdomyolysis: A Case Report Long-Segment Epidural Hemorrhage of the Cervical and Dorsal Spine: A Case Report of a Rare Complication of Dengue Virus Disease A Critical Analysis of Intracranial Hemorrhage (ICH) as a Fatal Complication of Dengue Fever Therapeutic plasma exchange and … Read more

Chronic subdural hematoma treatment Kampo Medicine for Neurological Diseases Correlation between Blood Type 0 and Risk of Chronic Subdural Hematoma Recurrence: A Single Center Retrospective Cohort Study Outcomes of SUBGALEAL Drain Placement after two Burr-Holes Craniectomy for Chronic Subdural Hematoma Middle meningeal artery embolization for the management of chronic subdural hematoma: what a difference a … Read more

AO Spine Upper Cervical Injury Classification System Latest AO Spine Upper Cervical Injury Classification System PubMed related Articles The Reliability of the AO Spine Upper Cervical Classification System in Children: Results of a Multi-Center Study Global Validation of the AO Spine Upper Cervical Injury Classification: Geographic Region Affects Reliability and Reproducibility The AO spine upper … Read more

Aneurysmal subarachnoid hemorrhage outcome Latest PubMed aneurysmal subarachnoid hemorrhage outcome related Articles Association Between Chronic Hypertension and the Risk of 12 Cardiovascular Diseases Among Parous Women: The Role of Adverse Pregnancy Outcomes Prompt closure versus gradual weaning of external ventricular drainage for hydrocephalus following aneurysmal subarachnoid haemorrhage: Protocol for the DRAIN randomised clinical trial Hemodynamic … Read more

Basal ganglia hemorrhage surgery Latest Pubmed Related Articles Laser navigation combined with XperCT technology-assisted puncture of basal ganglia intracerebral hemorrhage Early Minimally Invasive Removal of Intracerebral Hemorrhage (ENRICH): Study protocol for a multi-centered two-arm randomized adaptive trial Honokiol attenuates mitochondrial fission and cell apoptosis by activating Sirt3 in intracerebral hemorrhage Newly Diagnosed Adult Basal Ganglia … Read more

Superior sagittal sinus dural arteriovenous fistula Latest Pubmed Related Articles Sinus reconstruction therapy for superior sagittal sinus dural arteriovenous fistula caused by parasagittal meningioma invasion: a case report Acute traumatic dural arteriovenous fistula of the superior sagittal sinus: illustrative case Developmental venous anomaly associated with dural arteriovenous fistula: Etiopathogenesis and hemorrhagic risk Spontaneous closure of … Read more

Glioblastoma J.Sales-Llopis Neurosurgery Service, Alicante University General Hospital, Spain. Definition While glioblastoma was historically classified as isocitrate dehydrogenase (IDH)-wildtype and IDH-mutant groups, the Consortium to Inform Molecular and Practical Approaches to CNS Tumor Taxonomy (cIMPACT-NOW) and the World Health Organization Classification of Tumors of the Central Nervous System 2021 clearly updated the nomenclature to reflect glioblastoma to be compatible with wildtype IDH status … Read more

Pituitary neuroendocrine tumor Latest Pubmed Related Articles Evidence for an intra-tumoral microbiome in pituitary neuroendocrine tumors with different clinical phenotypes Evaluation of the Value of Perfusion-Weighted Magnetic Resonance Imaging in the Differential Diagnosis of Sellar and Parasellar Tumors Functioning Endocrine Outcome after Endoscopic Endonasal Transsellar Approach for Pituitary Neuroendocrine Tumors Pituitary Tumorigenesis-Implications for Management Diagnosis … Read more

Aneurysmal subarachnoid hemorrhage (aSAH) Type of spontaneous subarachnoid hemorrhage. Aneurysmal subarachnoid hemorrhage algorithm see Aneurysmal subarachnoid hemorrhage algorithm. Classification Aneurysmal subarachnoid hemorrhage classification. Miscellaneous facts about SAH Subarachnoid hemorrhage (SAH) following aneurysm bleeding accounts for 6% to 8% of all cerebrovascular accidents. The anterior communicating artery aneurysm cause aneurysmal subarachnoid hemorrhage, about 21.0%~25.5% of percent of spontaneous subarachnoid hemorrhage 1) 2) 3). The peak age for … Read more

Subarachnoid hemorrhage (SAH) A subarachnoid hemorrhage is a hemorrhage in the subarachnoid space. Subarachnoid hemorrhage (SAH) is a medical emergency that requires immediate intervention. The etiology varies between cases; however, rupture of an intracranial aneurysm accounts for 80% of medical emergencies. Early intervention and treatment are essential to prevent long-term complications. Over the years, treatment of SAH has … Read more

Adamantinomatous craniopharyngioma diagnosis Latest Pubmed Related Articles Clinical features of pituitary or parasellar tumor onset with cranial nerve palsy: surgical intervention considerations Obesity mechanism after hypothalamic damage: Cohort analysis of neuroimaging, psychological, cognitive, and clinical phenotyping data Single-cell RNA sequencing highlights intratumor heterogeneity and intercellular network featured in adamantinomatous craniopharyngioma Persistent severe visual field impairment … Read more

Anterior communicating artery see anterior communicating artery aneurysm. Connect one anterior cerebral artery with the other, within and along the floor of the cerebral vault. The local anatomy of the anterior communicating artery aneurysms is very complex and there are 13 arteries in them. ACCEPTED ANATOMIC STUDIES have indicated that the anterior communicating artery has no branches or … Read more

Burr hole trephination for chronic subdural hematoma Effect of postoperative tranexamic acid on recurrence rate and complications in chronic subdural hematomas patients: preliminary results of a randomized controlled clinical trial Non-traumatic Chronic Subdural Hematoma With Myelodysplastic Syndrome: A Case Report Development and validation of a recurrent prediction model for patients with unilateral chronic subdural hematoma … Read more

Balamuthia amoebic encephalitis A clinical case report of Balamuthia granulomatous amoebic encephalitis in a non-immunocompromised patient and literature review <em>Balamuthia mandrillaris</em> Encephalitis Presenting as a Symptomatic Focal Hypodensity in an Immunocompromised Patient Pathogenic free-living amoebic encephalitis from 48 cases in China: A systematic review Amebic Meningoencephalitis Successful Treatment of Balamuthia mandrillaris Granulomatous Amebic Encephalitis with … Read more

Brain invasion in atypical meningioma J.Sales-Llopis Neurosurgery Service, Alicante University General Hospital, Alicante, Spain. Latest Pubmed Related Articles Brain Invasion and Trends in Molecular Research on Meningioma Pediatric meningioma with rhabdoid features developed at the site of skull fracture: illustrative case Radiation therapy for atypical and anaplastic meningiomas: an overview of current results and controversial … Read more

Cerebral cavernous malformation J.Sales-Llopis Neurosurgery Service, Alicante University General Hospital, Alicante, Spain. Latest Pubmed Related Articles Amplification of protease-activated receptors signaling in sporadic cerebral cavernous malformation endothelial cells Impaired retinoic acid signaling in cerebral cavernous malformations Cranial ultrasonography in diagnosis of infantile cerebral cavernous malformation Pediatric Cerebral Cavernous Malformation: A Single-Centered Experience of 23 Cases … Read more

Cingulate gyrus glioma J.Sales-Llopis, J.Abarca-Olivas, P.González-López Neurosurgery Department, University General Hospital of Alicante, Spain Latest Pubmed Related Articles Microsurgical anatomy of the isthmic cingulum: a new white matter crossroad and neurosurgical implications in the posteromedial interhemispheric approaches and the glioma invasion patterns Structural alterations of the salience network in patients with insular glioma Applied Fence-Post Techniques Using … Read more

Chronic subdural hematoma J.Sales-Llopis Neurosurgery Department, University General Hospital of Alicante, Spain Latest Pubmed Related Articles Surgical treatment for chronic subdural hematoma in the elderly: A retrospective analysis Prediction of the prognosis of chronic/subacute subdural hematoma based on the ratio of volume to surface area Clinical Outcome and Recurrence Risk of Chronic Subdural Hematoma After … Read more

Superficial temporal artery to middle cerebral artery bypass for moyamoya disease Is STA really a low-flow graft? A quantitative ultrasonographic study of the flow of STA for cerebral revascularization in MMD patients Sonolucent Cranioplasty in Extracranial to Intracranial Bypass Surgery: Early Multicenter Experience of 44 Cases Surgical revascularization for quasi-moyamoya disease associated with polyneuropathy, organomegaly, … Read more

Chronic subdural hematoma after ventriculoperitoneal shunt overdrainage Chronic subdural hematoma caused by excessive drainage in a patient with ventriculoperitoneal shunt valve breakdown in brain injury: a case report Subdural Lesions Linking Additional Intracranial Spaces and Chronic Subdural Hematomas: A Narrative Review with Mutual Correlation and Possible Mechanisms behind High Recurrence Lumbo-Peritoneal Shunt for Patients with … Read more

Convexity meningioma J.Sales-Llopis Neurosurgery Service, Alicante University General Hospital, Spain. Latest Pubmed Related Articles Predictive factors for post operative seizures following meningioma resection in patients without preoperative seizures: a multicenter retrospective analysis Post-operative gamma knife radiosurgery for WHO grade I intracranial meningiomas: A single-center, retrospective study Prognosis and histology of sporadic synchronous and metachronous meningiomas … Read more

Trigeminal neuralgia Latest Pubmed Related Articles Locus coeruleus-noradrenergic modulation of trigeminal pain: Implications for trigeminal neuralgia and psychiatric comorbidities An unusual finding of the Porus trigeminus: Case report with histological findings Analysis of potential pathogenic factors of trigeminal neuralgia in rats Commentary: Increase in Trigeminal Nerve Cross-Sectional Area on Immediate Postoperative MRI Predicts Favorable Outcome … Read more

Flow Diverter Stent for Middle Cerebral Artery Aneurysm Safety and efficacy of flow diverter stents in the treatment of middle cerebral artery aneurysms: a single-center experience and follow-up data Recurrent reversible in-stent-stenosis after flow diverter treatment Magnetic resonance perfusion imaging findings following flow diversion in patients with complex middle cerebral artery bifurcation aneurysms: a single-center … Read more

Regorafenib side effects   Latest Pubmed Related Articles Radiosurgery and Stereotactic Brain Radiotherapy with Systemic Therapy in Recurrent High-Grade Gliomas: Is It Feasible? Therapeutic Strategies in Recurrent High-Grade Gliomas Regorafenib for recurrent high-grade glioma: a unicentric retrospective analysis of feasibility, efficacy, and toxicity Efficacy and tolerability of regorafenib in pretreated patients with progressive CNS grade … Read more

Corpus callosum The corpus callosum (from Latin: “tough body”), also known as the colossal commissure, is a wide, flat bundle of neural fibers beneath the cortex in the eutherian brain at the longitudinal fissure. It connects the left and right cerebral hemispheres and facilitates interhemispheric communication. It is the largest white matter structure in the brain, consisting of 200–250 … Read more

Microvascular Decompression Complications Latest Pubmed Related Articles Commentary: Facial Nerve Massage for the Treatment of Hemifacial Spasm Refractory to Microvascular Decompression: Outcomes and Complications Microvascular decompression for young onset primary trigeminal neuralgia: a single-center experience Outcomes after microvascular decompression for sole arterial versus venous compression in trigeminal neuralgia Effective Control of Postoperative Cerebrospinal Fluid Leakage … Read more

Neurosurgical Residency Away Rotation Neurosurgical Residency Away Rotation is an important component in the education of a neurosurgical resident. Subspecialization of physicians and regional centers concentrate the volume of certain rare cases into fewer hospitals. Consequently, the primary institution of a Neurosurgical Resident Training Program may not have sufficient case volume to meet the current Residency Review Committee case minimum requirements in some areas. To ensure the competency of graduating residents through comprehensive neurosurgical education, programs may need residents … Read more

Neurosurgical Training in Germany There has been a fivefold increase in neurosurgeons over the last three decades in Germany, despite a lesser increase in operations. Currently, there are approximately 1000 neurosurgical residents employed at training hospitals. Neurosurgery remains an attractive specialty in Germany, but there are two concerns that may impede its appeal in the near future. The administrative burden … Read more

Olfactory groove meningioma Olfactory groove meningiomas (OGMs) are arachnoid cell neoplasms of the frontoethmoidal suture and lamina cribrosa, 1) and may involve any part of the area from the crista galli to the planum sphenoidale 2) 3) 4). Epidemiology Olfactory groove meningioma epidemiology Classification Olfactory groove meningioma classification Clinical features Olfactory groove meningioma clinical features Diagnosis Olfactory groove meningioma diagnosis. Differential diagnosis Tuberculum sellae meningioma Planum sphenoidale meningioma Treatment … Read more

3D Exoscope for Vascular neurosurgery Neurovascular microsurgical experience through 3D exoscopy. Case report and literature review Microvascular anastomosis in a challenging setting using a 4 K three-dimensional exoscope compared with a conventional microscope: An <em>in vivo</em> animal study 3D Exoscopes are Noninferior to Operating Microscopes in Aneurysm Surgery: Comparative Single-Surgeon Series of 52 Consecutive Cases Case … Read more

Parkinson’s disease Mechanisms of 1Hz inhibitory and 5Hz excitatory repetitive transcranial magnetic stimulations in Parkinson’s Disease- An fMRI study Neurotrophin mimetics and tropomyosin kinase receptors: a futuristic pharmacological tool for Parkinson’s Inner retinal layers’ alterations of the microvasculature in early stages of Parkinson’s disease: a cross sectional study Distinct phenotypes of stimulation-induced dysarthria represent different … Read more

Norwegian Registry for Spine Surgery (NORspine) https://helsedata.no/en/forvaltere/university-hospital-of-north-norway/norwegian-registry-for-spine-surgery/ Latest Pubmed Related Articles Characteristics and outcomes of patients who did not respond to a national spine surgery registry Postoperative Dural Sac Cross-sectional Area as an Association for Outcome after Surgery for Lumbar Spinal Stenosis. Clinical and Radiological Results from the Nordsten-spinal Stenosis Trial Return to work after … Read more

Condoliase for lumbar disc herniation Latest Pubmed Related Articles Short-term clinical and radiographic outcomes of chemonucleolysis with condoliase for painful lumbar disc herniation and analysis regarding intradiscal injection area Cost-effectiveness analysis of intradiscal condoliase injection vs. surgical or conservative treatment for lumbar disc herniation Predictive Factors for Poor Outcome following Chemonucleolysis with Condoliase in Lumbar … Read more

Degenerative cervical myelopathy J.Sales-Llopis Neurosurgery Service, Alicante University General Hospital, Alicante, Spain. The assessment, diagnosis, operative and nonoperative management of degenerative cervical myelopathy (DCM) have evolved rapidly over the last 20 years. A clearer understanding of the pathobiology of DCM has led to attempts to develop objective measurements of the severity of myelopathy, including technology … Read more

Deep brain stimulation of the nucleus accumbens for alcohol use disorder Deep brain stimulation of the nucleus accumbens in treatment-resistant alcohol use disorder: a double-blind randomized controlled multi-center trial Deep brain stimulation of the nucleus accumbens in the treatment of severe alcohol use disorder: a phase I pilot trial Deep Brain Stimulation in Drug Addiction … Read more

SMAD6 (SMAD Family Member 6) is a Protein Coding gene. It belongs to the SMAD family of signaling molecules. It acts as an inhibitory SMAD, meaning that it negatively regulates signaling pathways activated by transforming growth factor-beta (TGF-beta) and bone morphogenetic proteins (BMPs). SMAD6 plays a role in various biological processes such as cell proliferation, … Read more

Stroke guidelines There are multiple stroke guidelines globally. To synthesize these and summarize what existing stroke guidelines recommend about the management of people with stroke, the World Stroke Organization (WSO) Guideline committee, under the auspices of the WSO, reviewed available guidelines. They identified areas of strong agreement across guidelines, and their global coverage. To systematically review the literature to identify stroke guidelines (excluding primary stroke prevention and subarachnoid … Read more

Idiopathic normal pressure hydrocephalus Magnetic resonance imaging Latest Pubmed Related Articles Resting-state functional-MRI in iNPH: can default mode and motor networks changes improve patient selection and outcome? Preliminary report Association of right precuneus compression with apathy in idiopathic normal pressure hydrocephalus: a pilot study Patients with heterozygous HTRA1-related cerebral small vessel disease misdiagnosed with other … Read more

Pregnant neurosurgical resident It is possible for a neurosurgical resident to be pregnant, as there are no specific restrictions on pregnant individuals becoming or remaining neurosurgical residents. However, pregnant residents may need to make accommodations for their pregnancy, such as modifying their work schedule or duties, in order to ensure the safety of both the resident and the patient. It is important … Read more

Central nervous system tumor guidelines NCCN Guidelines The NCCN Guidelines for Central nervous system tumor focus on the management of the following adult CNS cancers: glioma (WHO grade 1, WHO grade 2-3 Oligodendroglioma IDH-mutant and 1p/19q-codeleted, WHO grade 2-4 Astrocytoma IDH-mutants, WHO grade 4 glioblastoma), intracranial and spinal ependymomas, medulloblastoma, limited and extensive brain metastases, leptomeningeal metastases, non-AIDS-related Primary central nervous system lymphomas, metastatic spine tumors, meningiomas, and primary spinal cord tumors. … Read more

Brain metastases Investigating the role of delayed contrast magnetic resonance imaging (MRI) to differentiate radiation necrosis from tumour recurrence in brain metastases after stereotactic radiosurgery The Effects of Supportive Caring on Symptoms Distress, Nursing Needs, and Depression in Patients With Brain Tumor After Surgery: A Preliminary Study Efficacy and safety comparison of PD-1 inhibitors <em>vs.</em> … Read more

Cerebellar mutism Clinical characteristics and prognosis of Glioblastoma patients with infratentorial recurrence The importance of olivary hypertrophic degeneration as a differential diagnosis in cerebellar mutism syndrome Cerebellar mutism syndrome: From pathophysiology to rehabilitation A presurgical voxel-wise predictive model for cerebellar mutism syndrome in children with posterior fossa tumors Postoperative MRI features of cerebellar mutism syndrome: … Read more

Tranexamic acid for intracranial meningioma Latest Pubmed Articles A systematic review and meta-analysis of the effects of tranexamic acid in surgical procedure for intracranial meningioma Myocardial infarction after craniotomy for asymptomatic meningioma Safety of intravenous tranexamic acid in patients undergoing supratentorial meningiomas resection: protocol for a randomised, parallel-group, placebo control, non-inferiority trial Effect of tranexamic … Read more

Radiation necrosis diagnosis Latest Pubmed Related Articles Radiation necrosis or tumor progression? A review of the radiographic modalities used in the diagnosis of cerebral radiation necrosis A phase III, multicenter, randomized controlled trial of preoperative versus postoperative stereotactic radiosurgery for patients with surgically resectable brain metastases VEGFR-TKI treatment for radiation-induced brain injury after gamma knife … Read more

NFTI-QOL The NFTI-QOL is a robustly constructed disease-specific QOL questionnaire for neurofibromatosis type 2. It correlates strongly and significantly with EuroQOL and all SF-36 domains (p < 0.01). It is straightforward and quick (≤3 minutes) for patients to complete and easy to score. It is suitable as a quantitative method of assessing QOL in NF2 both in a clinical setting and as an outcome measure … Read more

Intracranial Aneurysm (IA) Natural history see Intracranial Aneurysm Natural history History see Intracranial Aneurysm History. Epidemiology see Intracranial Aneurysm Epidemiology. Classification see Intracranial Aneurysm classification. Pathogenesis see Intracranial aneurysm pathogenesis. Computational fluid dynamics see Computational fluid dynamics for intracranial aneurysm Risk Factors Intracranial aneurysm risk factors. Clinical features The clinical presentation is varied, ranging from asymptomatic lesions to those presenting with … Read more

The role of major journals publishing the results of randomized controlled trials (RCTs) is crucial. This is because, when results are published in a major journal, the study receives “…the journal’s stamp of approval”, the published results carry a kind of professional approbation, and the paper becomes more attractive to both the readers and media, who may amplify the real value … Read more

Anterior sacral meningocele Anterior sacral meningoceles are congenital lesions that consist of a spinal fluid-filled sac in the pelvis communicating by a small neck with the spinal subarachnoid space through a defect in the sacrum. They protrude into retroperitoneal and presacral space. 1) 2). The wall of the sac consists of two layers, an inner arachnoid membrane … Read more

Preoperative Embolization for Brain Arteriovenous Malformation Latest Pubmed Related Articles Head-Mounted Augmented Reality in the Planning of Cerebrovascular Neurosurgical Procedures: A Single-Center Initial Experience Microsurgery versus Microsurgery With Preoperative Embolization for Brain Arteriovenous Malformation Treatment: A Systematic Review and Meta-analysis Treatment of high-grade brain arteriovenous malformations using a hybrid operating room: A prospective single-arm study … Read more

1p/19q co-deletion Latest Pubmed Related Articles The Role of Neuro-Inflammation and Innate Immunity in Pathophysiology of Brain and Spinal Cord Tumors Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes A Patient With Epilepsy, Ganglioglioma, and Oligodendroglioma With Anaplastic Foci in the Same Left Frontoparietal Lesion: A Case Report Clinical Benefit of Bevacizumab and … Read more

Cervical Sympathetic Nerve Block for cerebral vasospasm Sympathetic perivascular nerve fibers originate from the superior cervical ganglion (SCG) to innervate the cerebral vasculature, with activation resulting in vasoconstriction. Sympathetic pathways are thought to be a significant contributor to cerebral vasospasm 1). A simple treatment such as a cervical sympathetic nerve block may be an effective therapy but is not routinely performed as cerebral vasospasm treatment/DCI. … Read more

Delirium Diagnosis Quality Improvement in Delirium Health Literacy in Older Adult Patients and Their Caregivers Attending a Geriatric Clinic The Effect of Consultation-Liaison Psychiatry on Postoperative Delirium in Elderly Hip Fracture Patients in the General Hospital Pulsatile Femoral Vein Doppler and Congestive Delirium, What Is the Relationship?: A Case Report General Anesthesia in a Patient … Read more

Spinal cord injury epidemiology Latest The Importance of Prospective Registries and Clinical Research Networks in the Evolution of Spinal Cord Injury Care Pediatric Cervical Spine Injuries Molecular and cellular changes in the post-traumatic spinal cord remodeling after autoinfusion of a genetically-enriched leucoconcentrate in a mini-pig model Traumatic Thoracic and Lumbar Spine Injury in Adult Population … Read more

Brain abscess J.Sales-Llopis Neurosurgery Service, Alicante University General Hospital, Alicante Institute for Health and Biomedical Research (ISABIAL – FISABIO Foundation), Alicante, Spain. A brain abscess is a focal area of necrosis starting in an area of cerebritis surrounded by a membrane. Brain abscesses are suppurative infections of the brain parenchyma surrounded by a vascularized capsule. see also Intracranial abscess. It is a potentially life-threatening condition requiring … Read more

Trigone ventricular meningioma Prophylactic Intraventricular Piping Method Prevents Entrapped Temporal Horn After Removal of Ventricle Trigone Meningioma: Technical Note Risk Factors of Postoperative Meningitis in Lateral Ventricular Trigone Meningiomas: A Clinical Analysis of 64 Patients Massive intracranial hemorrhage caused by intraventricular meningioma: case report Quiescent and Activated Fibroblasts in Lateral Ventricular Meningioma With a Dura-like … Read more

 Table of Contents  Linezolid in Neurosurgery Latest articles Case series References Linezolid in Neurosurgery Latest articles Diagnosis and Treatment to a Post-Craniotomy Intracranial Infection Caused by Corynebacterium Nocardia farcinica pituitary abscess in an immunocompetent patient: illustrative case Experience with enterococcal meningitis/ventriculitis in children Analysis of the management of ventriculitis cases at a UK neurosurgery centre … Read more

Frontal sinus cranialization Algorithms for the management of frontal sinus fractures: A retrospective study A Clinical Case of Delayed Posttraumatic Frontal Sinus Cerebrospinal Fluid Leakage Management Via External Surgical Approach Management of Frontal Bone Fracture in a Tertiary Neurosurgical Care Center-A Retrospective Study Frontal Sinus Fractures: A Contemporary Approach in the Endoscopic Era Frontal Cranioplasty … Read more

Cerebellar pilocytic astrocytoma Latest news Key concepts ● Often cystic, half of these have a mural nodule. ● Usually presents during the second decade of life (ages 10–20 yrs). ● A subtype of pilocytic astrocytoma. Formerly referred to by the nonspecific and confusing term cystic cerebellar astrocytoma. Epidemiology Cerebellar pilocytic astrocytoma epidemiology. Classification Children see Cerebellar pilocytic astrocytoma in children. … Read more

Microvascular decompression for hemifacial spasm Routine postoperative admission to the neurocritical intensive care unit after microvascular decompression: necessary or can it be abandoned? Correction to: The value of intraoperative indocyanine green angiography in microvascular decompression for hemifacial spasm to avoid brainstem ischemia Hemifacial Spasm Caused by Distal Neurovascular Compression Confirmed by Lateral Spread Response Monitoring … Read more

Pediatric traumatic brain injury outcome see also Traumatic brain injury outcome. Latest articles Withdrawal of life sustaining therapies in children with severe traumatic brain injury Prediction Models for Neurocognitive Outcome of Mild Traumatic Brain Injury in Children: a Systematic Review Low morbidity and mortality in children with severe traumatic brain injury treated according to the Lund … Read more

Rongeur A rongeur is a strongly constructed instrument with a sharp-edged, scoop-shaped tip, used for gouging out bone. Rongeur is a French word that means rodent or ‘gnawer’. A rongeur can be used to open a window in bone, often in the skull. It is used in neurosurgery, podiatric surgery, and orthopedic surgery to expose areas for … Read more

Hemorrhagic transformation Large areas of hemorrhagic transformation within an ischemic infarct may be more indicative of cardiogenic brain embolism (CBE) due to thrombolysis of the clot and reperfusion of infarcted brain with the subsequent hemorrhagic conversion. Hemorrhagic transformation most often occurs within 48 hrs of a CBE stroke, and is more common with larger strokes. Intraarterial thrombolysis within 6 hours of stroke onset may increase recanalization rates to … Read more

Mechanical thrombectomy outcome Clinical trials have shown that mechanical thrombectomy (MT) is associated with improved functional outcomes for patients with acute ischemic stroke presenting with proximal anterior circulation, large vessel occlusion, and salvageable brain tissue 1) 2) 3) 4) 5). Stroke patients who underwent successful thrombectomy with general anesthesia achieved higher rates of functional independence when procedural ETCO2 exceeded 35 mmHg. Further studies to confirm this effect and investigate optimal ETCO2 parameters should … Read more