Despite good outcomes from high-quality clinical trials, referrals of patients with seizures refractory to medical treatment remain infrequent 1).
Three RCTs (two adult RCTs and one pediatric RCT) consistently supported the efficacy of resective surgery as treatment for epilepsy with semiology localized to the mesial temporal lobe. In these studies, 58-100% of the patients who underwent resective surgery achieved seizure freedom, in comparison to 0-13% of medically treated patients. In another RCT, the likelihood of seizure freedom after resective surgery was independent of the surgical approach (transSylvian [64%] versus subtemporal [62%]). Two other RCTs demonstrated that hippocampal resection is essential to optimize seizure control. But, no significant gain in seizure control was achieved beyond removing 2.5 cm of the hippocampus. Across RCTs, minor complications (deficit lasting < 3 months) and major complications (deficit > 3 months) ranged 2-5% and 5-11% respectively. However, nonincapacitating superior subquadrantic visual-field defects (not typically considered a minor or major complication) were noted in up to 55% of the surgical cohort. The available RCTs provide compelling support for resective surgery as a treatment for mesial temporal lobe epilepsy and offer insights toward optimal surgical strategy 2)
Complete removal of the epileptogenic zone significantly increases the chances for postoperative seizure-freedom. In complex surgical candidates, delineation of the epileptogenic zone requires a long-term invasive video/EEG from intracranialelectrodes. It is especially challenging to achieve a complete resection in deep brain structures such as opercular insular cortex3).
Case series
Belohlavkova et al. retrospectively reviewed data of pediatric patients operated in Motol Epilepsy Center between October 2010 and June 2020 who underwent resections guided by intraoperative visual detection of depth electrodes following SEEG. The outcome in terms of seizure- and AED-freedom was assessed individually in each patient.
Nineteen patients (age at surgery 2.9-18.6 years, median 13 years) were included in the study. The epileptogenic zone involved opercular insular cortex in eighteen patients. The intraoperative detection of the electrodes was successful in seventeen patients and the surgery was regarded complete in sixteen. Thirteen patients were seizure-free at final follow-up including six drug-free cases. The successful intraoperative detection of the electrodes was associated with favorable outcome in terms of achieving complete resection and seizure-freedom in most cases. On the contrary, the patients in whom the procedure failed had poor postsurgical outcome.
The reported technique helps to achieve the complete resection in challenging patients with the epileptogenic zone in deep brain structures 4)
81 patients with tuberous sclerosis complex (TSC) who had undergone resective epilepsy surgery at Sanbo Brain Hospital, between April 2004 and June 2019. They estimated the cumulative probability of remaining seizure-free and plotted survival curves. Variables were compared using Mann-Whitney U, Pearson’s correlation, continuity correction, and Fisher’s exact chi-square tests. Prognostic predictors were analyzed using log-rank (Mantel-Cox) tests and Cox regression models.
At the last follow-up, 48 (59.3%) patients were classified as International League Against Epilepsy Class 1 (including 14 patients who had seizures <3 times postoperatively on the same or different day and were seizure-free at all other times). The estimated cumulative probability of remaining seizure-free postoperatively was 69.0% (95% confidence interval [CI] 58.8-79.2%), 61.9% (95% CI 51.1-72.7%), and 55.0% (95% CI 42.8-67.2%) at 2, 5, and 10 years, respectively. The mean time of remaining seizure-free was 7.24 ± 0.634 years (95% CI 6.00-8.49); en bloc resection was an essential positive predictor of postoperative seizure freedom, as was age at seizure onset, regional interictal video-electroencephalography pattern, and temporal lobe surgery. The longer the seizure-free time, the less likely a relapse. Patients who postoperatively experienced seizures remained likely to recover.
Belohlavkova A, Jahodova A, Kudr M, Benova B, Ebel M, Liby P, Taborsky J, Jezdik P, Janca R, Kyncl M, Tichy M, Krsek P. May intraoperative detection of stereotactically inserted intracerebral electrodes increase precision of resective epilepsy surgery? Eur J Paediatr Neurol. 2021 Sep 25;35:49-55. doi: 10.1016/j.ejpn.2021.09.012. Epub ahead of print. PMID: 34610561.
Huang Q, Zhou J, Wang X, Li T, Wang M, Wang J, Teng P, Qi X, Zhu M, Luan G, Zhai F. Predictors and Long-term Outcome of Resective Epilepsy Surgery in Patients with Tuberous Sclerosis Complex: A Single-centre Retrospective Cohort Study. Seizure. 2021 Mar 25;88:45-52. doi: 10.1016/j.seizure.2021.03.022. Epub ahead of print. PMID:
Factors influencing outcomes of the treatment of positional plagiocephaly in infants: a 7-year experience
While this has been successful in reducing SIDS, it has also resulted in a substantial increase in the prevalence of positional skull deformity. Read More
FREE
Factors influencing outcomes of the treatment of positional plagiocephaly in infants: a 7-year experience
Sandi Lam, MD, MBA1, I-Wen Pan, PhD1, Ben A. Strickland, MD1, Caroline Hadley, MD1, Bradley Daniels, BS1, Jim Brookshier, CPO, LPO2, and Thomas G. Luerssen, MD1 1Department of Neurosurgery/Division of Pediatric Neurosurgery, Texas Children’s Hospital/Baylor College of Medicine; and 2Hanger Clinic, Houston, Texas
The health belief model and factors associated with adherence to treatment recommendations for positional plagiocephaly
Sandi Lam, MD, MBA1, Thomas G. Luerssen, MD1, Caroline Hadley, MD1, Bradley Daniels, BS1, Ben A. Strickland, MD1, Jim Brookshier, CPO, LPO2, and I-Wen Pan, PhD1 1Department of Neurosurgery/Division of Pediatric Neurosurgery, Texas Children’s Hospital/Baylor College of Medicine; and 2Hanger Orthotics, Houston, Texas
Preoperative transdural collateral vessels in moyamoya as radiographic biomarkers of disease
Armide Storey, BS1, R. Michael Scott, MD1, Richard Robertson, MD2, and Edward Smith, MD1Departments of 1Neurosurgery and 2Radiology, Boston Children’s Hospital and Harvard Medical School, Boston, Massachusetts
Possible toxicity following embolization of congenital giant vertex hemangioma: case report
Ingrid Kieran, MD1, Zaitun Zakaria, MD2, Chandrasekaran Kaliaperumal, FRCSEd2, Declan O’Rourke, MRCP3, Alan O’Hare, FRCR4, Eoghan Laffan, FFR5, John Caird, FRCSI(SN)2, Mary D. King, FRCPI, FRCPCH3, and Dylan J. Murray, FRCS, FDS, FFD1Departments of 1Plastic and Craniofacial Surgery, 2Neurosurgery, 3Pediatric Neurology, and 5Radiology, Temple Street Children’s University Hospital; and 4Department of Neuroradiology, Beaumont Hospital, Dublin, Ireland
Correlations of atrial diameter and frontooccipital horn ratio with ventricle size in fetal ventriculomegaly
Jared M. Pisapia, MD1,2, Martin Rozycki, MS2, Hamed Akbari, MD, PhD2, Spyridon Bakas, PhD2, Jayesh P. Thawani, MD1, Julie S. Moldenhauer, MD3, Phillip B. Storm, MD1,4, Deborah M. Zarnow, MD5, Christos Davatzikos, PhD2, and Gregory G. Heuer, MD, PhD1,4 1Department of Neurosurgery; 2Center for Biomedical Image Computing and Analytics, University of Pennsylvania; 3Center for Fetal Diagnosis and Treatment, Special Delivery Unit; and Divisions of 4Neurosurgery and 5Neuroradiology, Children’s Hospital of Philadelphia, Pennsylvania
Hydrocephalus in a patient with an unruptured pial arteriovenous fistula: hydrodynamic considerations, endovascular treatment, and clinical course
Jesús A. Morales-Gómez, MD1, Vicente V. Garza-Oyervides, MD1, José A. Arenas-Ruiz, MD1, Mariana Mercado-Flores, MD2, C. Guillermo Elizondo-Riojas, MD, PhD2, Frederick A. Boop, MD3, and Ángel Martínez-Ponce de León, MD1 1Servicio de Neurocirugía and 2Centro Universitario de Imagen Diagnóstica, Hospital Universitario “Dr. José Eleuterio González,” Monterrey, Nuevo León, México; and 3Department of Neurosurgery, University of Tennessee Health Sciences Center, Memphis, Tennessee
Endonasal management of pediatric congenital transsphenoidal encephaloceles: nuances of a modified reconstruction technique. Technical note and report of 3 cases
Mehdi Zeinalizadeh, MD1,2, Seyed Mousa Sadrehosseini, MD3, Zohreh Habibi, MD4, Farideh Nejat, MD4, Harley Brito da Silva, MD5, and Harminder Singh, MD6 1Brain and Spinal Cord Injuries Repair and Research Center, 2Department of Neurological Surgery, and 3Department of Otolaryngology-Head & Neck Surgery, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences; and 4Department of Neurological Surgery, Children’s Medical Center, Tehran University of Medical Sciences, Tehran, Iran; 5Department of Neurological Surgery, Harborview Medical Center, University of Washington, Seattle, Washington; and 6Department of Neurological Surgery, Stanford University School of Medicine, Stanford, California
Report of effective trametinib therapy in 2 children with progressive hypothalamic optic pathway pilocytic astrocytoma: documentation of volumetric response
Catherine Miller, MD1, Daniel Guillaume, MD1, Kathryn Dusenbery, MD2, H. Brent Clark, MD, PhD3, and Christopher Moertel, MD4Departments of 1Neurosurgery, 2Radiation Oncology, 3Pathology, and 4Pediatric Hematology/Oncology, University of Minnesota, Minneapolis, Minnesota
Long-term follow-up of superior gluteal artery perforator flap closure of large myelomeningoceles
Brett A. Whittemore, MD1, Dale M. Swift, MD2, Bradley E. Weprin, MD2, and Frederick J. Duffy Jr., MD3Departments of 1Neurosurgery and 2Pediatric Neurosurgery, University of Texas Southwestern Medical Center, Dallas; and 3Department of Plastic Surgery, Medical City Hospital, Dallas, Texas
Solitary fibrous tumors of the spine: a pediatric case report with a comprehensive review of the literature
Gregory W. Albert, MD1,2, and Murat Gokden, MD3 1Division of Neurosurgery, Arkansas Children’s Hospital; and Departments of 2Neurosurgery and 3Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas
Clinical and surgical management of a congenital Type II split cord malformation presenting with progressive cranial neuropathies: case report
Patrick R. Maloney, MD1, Meghan E. Murphy, MD1, Molly J. Sullan, MS2, Kathryn M. Van Abel, MD2, Shelagh A. Cofer, MD2, John C. Cheville, MD3, and Nicholas M. Wetjen, MD1Departments of 1Neurosurgery, 2Otolaryngology, and 3Pathology, Mayo Clinic School of Medicine, Rochester, Minnesota
Interdural cavernous sinus dermoid cyst in a child: case report
Flavio Giordano, MD1, Giacomo Peri, MD1, Giacomo M. Bacci, MD, PhD2, Massimo Basile, MD3, Azzurra Guerra, MD4, Patrizia Bergonzini, MD4, Anna Maria Buccoliero, MD5, Barbara Spacca, MD1, Lorenzo Iughetti, MD, PhD4, PierArturo Donati, MD1, and Lorenzo Genitori, MD1 1Department of Neurosurgery, 2Neuro-ophthalmology Unit, 3Radiology Unit, and 5Pathology Unit, Anna Meyer Hospital, Firenze; and 4Department of Pediatrics, Ospedale Policlinico, University of Modena, Italy
Perioperative outcomes for pediatric neurosurgical procedures: analysis of the National Surgical Quality Improvement Program–Pediatrics
Benjamin J. Kuo, BS1,2,3, Joao Ricardo N. Vissoci, PhD1,2, Joseph R. Egger, PhD2, Emily R. Smith, PhD1,2, Gerald A. Grant, MD6, Michael M. Haglund, MD, PhD1,2,4, and Henry E. Rice, MD2,5 1Division of Global Neurosurgery and Neuroscience and 2Global Health Institute, Duke University, Durham, North Carolina; 3Duke-NUS Medical School, Singapore; Departments of 4Neurosurgery and 5Surgery, Duke University Medical Center, Durham, North Carolina; and 6Department of Neurosurgery, Stanford University, Stanford, California
María José Mayorga-Buiza, MD, PhD, Mónica Rivero-Garvía, MD, PhD, Javier Márquez-Rivas, MD, PhD, Carlos Velásquez-Rodríguez, MD, and Emilio Gómez-González, PhDHospital Universitario Virgen del Rocío, Seville, Spain; Marqués de Valdecilla Hospital, Santander, Spain; and Seville University, Engineering School, Seville, Spain
Letter to the Editor: Early seizure prophylaxis in pediatric severe traumatic brain injury: still a long way to go
Eduardo Mekitarian Filho, MD, MSc, PhDUniversity of São Paulo, São Paulo, Brazil
Pages 374-375
Response
Monica S. Vavilala, MD, Qian Qiu, MBA, Paige J. Ostahowski, BA, Nithya Kannan, MD, Douglas F. Zatzick, MD, Richard G. Ellenbogen, MD, Linda Ng Boyle, PhD, Pamela H. Mitchell, PhD, Mark S. Wainwright, MD, PhD, Richard B. Mink, MD, MACM, Jonathan I. Groner, MD, Michael J. Bell, MD, and Christopher C. Giza, MD
Miguel Gelabert-González, PhD, Eduardo Arán-Echabe, MD, and José María Santín-Amo, MDUniversity of Santiago de Compostela, Spain
Pages 375-376
Response
Joseph Lopez, MD, MBA, Alan Utria, MD, Regina S. Cho, BS, Gerhard S. Mundinger, MD, Craig Vander Kolk, MD, George I. Jallo, MD, Edward S. Ahn, MD, and Amir Dorafshar, MBChB
A novel technique to correct kyphosis in cervical myelopathy due to continuous-type ossification of the posterior longitudinal ligament
We aimed in this study to establish a new technique for the treatment of patients with cervical myelopathy that results from multilevel OPLL and kyphosis. Read More
Contralateral osteotomy of the pedicle and posterolateral elements for en bloc resection: a technique for oncological resection of posterolateral spinal tumors
Viren S. Vasudeva, MD1, Alexander E. Ropper, MD2, Samuel Rodriguez, MD3, Kyle C. Wu, MD1, and John H. Chi, MD, MPH1,4 1Department of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts; 2Department of Neurosurgery, Baylor College of Medicine, Houston, Texas; 3Department of Anesthesiology, Perioperative and Pain Medicine, Stanford University School of Medicine, Stanford, California; and 4Center for Neuro-Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts
Spine stereotactic radiosurgery for the treatment of multiple myeloma
Jacob A. Miller, BS1, Ehsan H. Balagamwala, MD2, Samuel T. Chao, MD2,3, Todd Emch, MD4, John H. Suh, MD2,3, Toufik Djemil, PhD5, and Lilyana Angelov, MD3,6 1Cleveland Clinic Lerner College of Medicine, 2Department of Radiation Oncology, 3Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, 4Department of Diagnostic Radiology, and 6Department of Neurosurgery, Cleveland Clinic, Cleveland, Ohio; and 5Department of Radiation Oncology, Cleveland Clinic Florida, Weston, Florida
Malignant peripheral nerve sheath tumors of the spine: results of surgical management from a multicenter study
Dean Chou, MD1, Mark H. Bilsky, MD2, Alessandro Luzzati, MD3, Charles G. Fisher, MD, MHSc4, Ziya L. Gokaslan, MD5, Laurence D. Rhines, MD6, Mark B. Dekutoski, MD7, Michael G. Fehlings, MD8, Ravi Ghag, MD4, Peter Varga, MD9, Stefano Boriani, MD10, Niccole M. Germscheid, MSc11, Jeremy J. Reynolds, MBChB12, and the AOSpine Knowledge Forum Tumor 1Department of Neurosurgery, University of California, San Francisco, California; 2Department of Neurosurgery, Memorial Sloan Kettering Cancer Center, New York, New York; 3Department of Orthopedics, Istituto Ortopedico Galeazzi, Milan, Italy; 4Department of Orthopaedics, University of British Columbia, Vancouver, Canada; 5Department of Neurosurgery, Brown University, Providence, Rhode Island; 6Department of Neurosurgery, MD Anderson Cancer Center, Houston, Texas; 7Department of Orthopedics, The CORE Institute, Phoenix, Arizona; 8Department of Neurosurgery, University of Toronto, Ontario, Canada; 9Department of Orthopedics, National Center for Spinal Disorders, Budapest, Hungary; 10Department of Orthopedics, The Rizzoli Institute, Bologna, Italy; 11AOSpine International, Davos, Switzerland; and 12Department of Orthopaedics, Oxford University Hospitals, Oxford, United Kingdom
Consensus guidelines for postoperative stereotactic body radiation therapy for spinal metastases: results of an international survey
Kristin J. Redmond, MD, MPH1, Simon S. Lo, MD2, Scott G. Soltys, MD3, Yoshiya Yamada, MD4, Igor J. Barani, MD5, Paul D. Brown, MD6, Eric L. Chang, MD7, Peter C. Gerszten, MD8, Samuel T. Chao, MD9, Robert J. Amdur, MD10, Antonio A. F. De Salles, MD, PhD11, Matthias Guckenberger, MD12, Bin S. Teh, MD13, Jason Sheehan, MD, PhD14, Charles R. Kersh, MD15, Michael G. Fehlings, MD, PhD, FRCSC16, Moon-Jun Sohn, MD, PhD17, Ung-Kyu Chang, MD18, Samuel Ryu, MD19, Iris C. Gibbs, MD3, and Arjun Sahgal, MD, FRCPC20 1Department of Radiation Oncology and Molecular Radiation Sciences, The John Hopkins University, Baltimore, Maryland; 2Department of Radiation Oncology, University Hospitals Seidman Cancer Center, Case Comprehensive Cancer Center; 9Department of Radiation Oncology, Rose Ella Burkhardt Brain Tumor and Neurooncology Center, Cleveland Clinic, Cleveland, Ohio; 3Department of Radiation Oncology, Stanford Cancer Institute, Stanford University, Stanford; 5Department of Radiation Oncology, University of California, San Francisco; 7Department of Radiation Oncology, Norris Cancer Center and Keck School of Medicine at University of Southern California; 11Department of Neurological Surgery, Brain Research Institute, University of California, Los Angeles, California; 4Department of Radiation Oncology, Memorial Sloan Kettering Cancer Center, New York; 19Department of Radiation Oncology, Stony Brook Cancer Center, Stony Brook, New York; 6Department of Radiation Oncology, MD Anderson Cancer Center; 13Department of Radiation Oncology, Houston Methodist Hospital, Cancer Center and Research Institute, Weill Cornell Medical College, Houston, Texas; 8Department of Neurological Surgery and Radiation Oncology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; 10Department of Radiation Oncology, University of Florida College of Medicine, Gainesville, Florida; 12Department of Radiation Oncology, University of Zurich, Switzerland; 14Department of Neurological Surgery, University of Virginia Health System, Charlottesville; 15Department of Radiation Oncology, Riverside Radiation Oncology Specialists, Newport News, Virginia; 16Division of Neurosurgery and Spine Program, Toronto Western Hospital, University of Toronto; 20Department of Radiation Oncology, Sunnybrook Health Sciences Center, University of Toronto, Toronto, Ontario, Canada; 17Department of Neurological Surgery, Radiosurgery Center, Inje University Ilsan Paik Hospital, College of Medicine, Goyang; and 18Department of Neurosurgery, Korea Institute of Radiological and Medical Sciences, Seoul, South Korea
Bilateral C-1 lateral mass reconstruction following radical resection of a giant osteoblastoma of the atlas: case report
Iulia Peciu-Florianu, MD1, Gopalakrishnan Chittur Viswanathan, MCh1, Juan Barges-Coll, MD1, Gabriel A. Castillo-Velázquez, MD4, Pierre-Yves Zambelli, MD, PhD2,3, and John M. Duff, MD1,3 1Neurosurgical Service, Department of Clinical Neurosciences and 2Division of Paediatric Orthopedics, University Hospital of Lausanne; 3Faculty of Biology and Medicine, University of Lausanne, Switzerland; and 4Neurosurgical Service, Centro Médico Puerta de Hierro, Guadalajara, Mexico
Radiofrequency ablation of spinal osteoid osteoma: a prospective study
Joe Faddoul, MD2, Yara Faddoul, MD1, Sandra Kobaiter-Maarrawi, PhD1, Ronald Moussa, MD2, Tony Rizk, MD2, Georges Nohra, MD2, Nabil Okais, MD2, Elie Samaha, MD2, and Joseph Maarrawi, MD, PhD1,2 1Laboratory of Neurosciences, Faculty of Medicine (PTS), St. Joseph University; and 2Department of Neurosurgery, Hôtel-Dieu de France Hospital, Beirut, Lebanon
Successful treatment of mixed yolk sac tumor and mature teratoma in the spinal cord: case report
Akitake Mukasa, MD, PhD1,, Shunsuke Yanagisawa, MD1, Kuniaki Saito, MD1, Shota Tanaka, MD1, Keisuke Takai, MD, PhD1,5, Junji Shibahara, MD, PhD2, Masachika Ikegami, MD3, Yusuke Nakao, MD3,6, Katsushi Takeshita, MD, PhD3,7, Masao Matsutani, MD, PhD4, and Nobuhito Saito, MD, PhD1Departments of 1Neurosurgery, 2Pathology, and 3Orthopaedic Surgery and Spinal Surgery, The University of Tokyo Hospital, Tokyo; and 4Department of Neuro-Oncology/Neurosurgery, Saitama Medical University International Medical Center, Hidaka, Japan
A novel technique to correct kyphosis in cervical myelopathy due to continuous-type ossification of the posterior longitudinal ligament
Dong-Ho Lee, MD, PhD, Youn-Suk Joo, MD, Chang Ju Hwang, MD, PhD, Choon Sung Lee, MD, PhD, and Jae Hwan Cho, MDDepartment of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea
Revisiting the differences between irreducible and reducible atlantoaxial dislocation in the era of direct posterior approach and C1–2 joint manipulation
Arsikere N. Deepak, MS1, Pravin Salunke, MCh1, Sushanta K. Sahoo, MCh1, Prashant K. Prasad, MS1, and Niranjan K. Khandelwal, MD2Departments of 1Neurosurgery and 2Radiodiagnosis, Postgraduate Institute of Medical Education and Research, Chandigarh, India
C-2 arteriovenous fistula presenting as a pathologic hangman’s fracture: case report
Rajeev D. Sen, BA, Carolina Gesteira Benjamin, MD, Howard A. Riina, MD, and Donato Pacione, MDNew York University School of Medicine, New York, New York
Lateral mass screw stimulation thresholds in posterior cervical instrumentation surgery: a predictor of medial deviation
Bayard Wilson, BA1,, Erik Curtis, MD2, Brian Hirshman, MD, MS2, Ahmet Oygar, MD2, Karen Chen, MD3, Brandon C. Gabel, MD2, Florin Vaida, PhD4, David W. Allison, PhD5, and Joseph D. Ciacci, MD2 1School of Medicine, 2Department of Neurosurgery, 3Department of Radiology, 4Department of Family Medicine and Public Health, Division of Biostatistics and Bio-informatics, and 5Department of Interventional Neurophysiology, University of California, San Diego, California
Lumbar decompression in the elderly: increased age as a risk factor for complications and nonhome discharge
Meghan E. Murphy, MD1,2, Hannah Gilder, BS1,2, Patrick R. Maloney, MD1,2, Brandon A. McCutcheon, MD, MPP1,2, Lorenzo Rinaldo, MD, PhD1,2, Daniel Shepherd, MD1,2, Panagiotis Kerezoudis, MD1,2, Daniel S. Ubl, MPH3, Cynthia S. Crowson, MS3, William E. Krauss, MD1, Elizabeth B. Habermann, PhD, MPH3, and Mohamad Bydon, MD1,2 1Department of Neurologic Surgery, Mayo Clinic; 2Mayo Clinic Neuro-Informatics Laboratory; and 3Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota
Multiple-hook fixation in revision spinal deformity surgery for patients with a previous multilevel fusion mass: technical note and preliminary outcomes
Ning Liu, MD1,3, and Kirkham B. Wood, MD1,2 1Department of Orthopaedic Surgery, Spine Service, Massachusetts General Hospital, Boston, Massachusetts; 2Department of Orthopaedic Surgery, Stanford University Medical Center, Redwood City, California; and 3Washington University in St. Louis, Brown School, St. Louis, Missouri
Diagnostic accuracy of motor evoked potentials to detect neurological deficit during idiopathic scoliosis correction: a systematic review
Parthasarathy D. Thirumala, MD1,3, Donald J. Crammond, PhD1, Yoon K. Loke, MBBS4, Hannah L. Cheng1, Jessie Huang1, and Jeffrey R. Balzer, PhD1,2Departments of 1Neurological Surgery and 2Neuroscience, University of Pittsburgh; 3Department of Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania; and 4Norwich Medical School, University of East Anglia, Norwich, United Kingdom
Spinal cord herniation repair with microstaples: case report
Pedro David Delgado-López, MD1, Cecilia Gil-Polo, MD, PhD1, Vicente Martín-Velasco, MD1, Javier Martín-Alonso, MD1, Ana María Galacho-Harriero, MD1, and Elena Araus-Galdós, MD2Departments of 1Neurosurgery and 2Neurophysiology, Hospital Universitario de Burgos, Spain
Bone marrow stromal cell sheets may promote axonal regeneration and functional recovery with suppression of glial scar formation after spinal cord transection injury in rats
Akinori Okuda, MD1,2, Noriko Horii-Hayashi, PhD2, Takayo Sasagawa, MS2, Takamasa Shimizu, MD, PhD1, Hideki Shigematsu, MD, PhD1, Eiichiro Iwata, MD, PhD1, Yasuhiko Morimoto, MD1, Keisuke Masuda, MD1, Munehisa Koizumi, MD, PhD3, Manabu Akahane, MD, PhD4, Mayumi Nishi, MD, PhD2, and Yasuhito Tanaka, MD, PhD1 1Department of Orthopaedic Surgery, Nara Medical University, Kashihara; 2Department of Anatomy and Cell Biology, Faculty of Medicine, Nara Medical University, Kashihara; 3Spine and Spinal Cord Surgery Center, Nara Prefecture General Medical Center; and 4Department of Public Health, Health Management, and Policy, Nara Medical University, Kashihara, Nara, Japan
Promotion of astrocytoma cell invasion by micro RNA–22 targeting of tissue inhibitor of matrix metalloproteinase–2
Yu-ichiro Ohnishi, MD, PhD1, Koichi Iwatsuki, MD, PhD1, Masahiro Ishihara, MD, PhD1, Toshika Ohkawa, MD, PhD2, Manabu Kinoshita, MD, PhD3, Koei Shinzawa, PhD4, Yasunori Fujimoto, MD, PhD1, and Toshiki Yoshimine, MD, PhD1Departments of 1Neurosurgery and 4Molecular Genetics, Osaka University Medical School; 2Department of Neurosurgery, Yao Municipal Hospital; and 3Department of Neurosurgery, Osaka Medical Center for Cancer and Cardiovascular Diseases, Osaka, Japan
Erratum: Screening via CT angiogram after traumatic cervical spine fractures: narrowing imaging to improve cost effectiveness. Experience of a Level I trauma center
Gabriel A. Smith, MDCase Western Reserve University School of Medicine, MetroHealth Medical Center, Cleveland, OH
Comparison of clipping and coiling in elderly patients with unruptured cerebral aneurysms
Since the publication of the International Subarachnoid Aneurysm Trial, which focused on ruptured aneurysms, there has been a paradigm shift in the treatment of cerebral aneurysms with an increased focus on coiling as the preferred intervention for patients with subarachnoid hemorrhage. Read More
Foramen magnum meningiomas: surgical results and risks predicting poor outcomes based on a modified classification
Da Li, MD1,2,3,4,, Zhen Wu, MD, PhD1,2,3,4, Cong Ren, MD1,2,3,4, Shu-Yu Hao, MD, PhD1, Liang Wang, MD, PhD1, Xin-Ru Xiao, MD, PhD1, Jie Tang, MD, PhD1, Yong-Gang Wang, MD, PhD1, Guo-Lu Meng, MD, PhD1, Li-Wei Zhang, MD, PhD1,2,3,4, and Jun-Ting Zhang, MD1,2,3,4 1Department of Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China; 2China National Clinical Research Center for Neurological Diseases; 3Center of Brain Tumor, Beijing Institute for Brain Disorders; and 4Beijing Key Laboratory of Brain Tumor, Beijing Tiantan Hospital, Capital Medical University, Beijing, People’s Republic of China
Body habitus, serum albumin, and the outcomes after craniotomy for tumor: a National Surgical Quality Improvement Program analysis
Hormuzdiyar H. Dasenbrock, MD1,2, Kevin X. Liu, DPhil2, Vamsidhar Chavakula, MD1,2, Christopher A. Devine, MPhil2, William B. Gormley, MD, MPH1,2, Elizabeth B. Claus, PhD, MD1,2,3, Timothy R. Smith, MD, PhD, MPH1,2, and Ian F. Dunn, MD1,2 1Department of Neurosurgery, Brigham and Women’s Hospital; 2Harvard Medical School, Boston, Massachusetts; and 3School of Public Health, Yale University, New Haven, Connecticut
Preoperative diagnosis of vagal and sympathetic cervical schwannomas based on radiographic findings
Christopher S. Graffeo, MD1, Kathryn M. Van Abel, MD2, Jonathan M. Morris, MD3, Matthew L. Carlson, MD2, Jamie J. Van Gompel, MD1, Eric J. Moore, MD2, Daniel L. Price, MD2, Jan L. Kasperbauer, MD2, Jeffrey R. Janus, MD2, Kerry D. Olsen, MD2, and Michael J. Link, MD1Departments of 1Neurologic Surgery, 2Otolaryngology–Head and Neck Surgery, and 3Radiology, Mayo Clinic, Rochester, Minnesota
Functional approach using intraoperative brain mapping and neurophysiological monitoring for the surgical treatment of brain metastases in the central region
Jose L. Sanmillan, MD1, Alejandro Fernández-Coello, MD1, Isabel Fernández-Conejero, MD2, Gerard Plans, MD1, and Andreu Gabarrós, MD, PhD1Departments of 1Neurosurgery and 2Neurophysiology, Hospital Universitari de Bellvitge, Barcelona, Spain
Quality of life is maintained using Gamma Knife radiosurgery: a prospective study of a brain metastases patient cohort
Bente Sandvei Skeie, MD, PhD1,2, Geir Egil Eide, PhD5,6, Marianne Flatebø1, Jan Ingeman Heggdal, MSc4, Elisabeth Larsen1, Sidsel Bragstad, MSc1, Paal-Henning Pedersen, MD, PhD1,2, and Per Øyvind Enger, MD, PhD1,3Departments of 1Neurosurgery and 4Oncology and Medical Physics, and 6Centre for Clinical Research, Haukeland University Hospital; and Departments of 2Clinical Medicine, 3Biomedicine, Oncomatrix Research Lab, and 5Global Public Health and Primary Care, University of Bergen, Norway
BRAF V600E mutation and BRAF kinase inhibitors in conjunction with stereotactic radiosurgery for intracranial melanoma metastases
Zhiyuan Xu, MD1, Cheng-Chia Lee, MD1,3,4, Arjun Ramesh, MD1, Adam C. Mueller, MD, PhD2, David Schlesinger, PhD1,2, Or Cohen-Inbar, MD, PhD1, Han-Hsun Shih, MD5, and Jason P. Sheehan, MD, PhD1,2Departments of 1Neurological Surgery and 2Radiation Oncology, University of Virginia, Charlottesville, Virginia; 3Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital; 4School of Medicine, National Yang-Ming University, Taipei; and 5Taichung Veterans General Hospital, Taichung, Taiwan, Republic of China
Impact of the radiosurgery prescription dose on the local control of small (2 cm or smaller) brain metastases
Alireza M. Mohammadi, MD1,2, Jason L. Schroeder, MD5, Lilyana Angelov, MD1,2, Samuel T. Chao, MD3, Erin S. Murphy, MD3, Jennifer S. Yu, MD, PhD3, Gennady Neyman, PhD3, Xuefei Jia, MS4, John H. Suh, MD3, Gene H. Barnett, MD1,2, and Michael A. Vogelbaum, MD, PhD1,2 1The Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Departments of 2Neurosurgery and 3Radiation Oncology, and 4Quantitative Health Science, Neurological Institute and Taussig Cancer Institute, Cleveland Clinic, Cleveland; and 5Department of Neurosurgery, University of Toledo Medical Center, Toledo, Ohio
Stereotactic radiosurgery for intracranial hemangiopericytomas: a multicenter study
Or Cohen-Inbar, MD, PhD1, Cheng-Chia Lee, MD2, Seyed H. Mousavi, MD3, Hideyuki Kano, MD, PhD3, David Mathieu, MD4, Antonio Meola, MD3, Peter Nakaji, MD5, Norissa Honea, PhD5, Matthew Johnson, MD6, Mahmoud Abbassy, MD7, Alireza M. Mohammadi, MD7, Danilo Silva, MD7, Huai-Che Yang, MD2, Inga Grills, MD6, Douglas Kondziolka, MD, MSc8, Gene H. Barnett, MD8, L. Dade Lunsford, MD3, and Jason Sheehan, MD, PhD1 1Department of Neurosurgery and Gamma Knife Center, University of Virginia Health System, Charlottesville, Virginia; 3Department of Neurosurgery, University of Pittsburgh, Pennsylvania; 5Department of Neurosurgery, Barrow Neurological Institute and St. Joseph’s Hospital and Medical Center, Phoenix, Arizona; 6Department of Radiation Oncology, Oakland University William Beaumont School of Medicine, Royal Oak, Michigan; 7Rose Ella Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic, Cleveland, Ohio; 8Department of Neurosurgery, New York University Langone Medical Center, New York, New York; 2Neurological Institute, Taipei Veterans General Hospital, and National Yang-Ming University, Taipei, Taiwan; and 4Department of Neurosurgery, University of Sherbrooke, Centre de Recherche Clinique Étienne-LeBel, Sherbrooke, Quebec, Canada
Factors predicting contralateral hematoma growth after unilateral drainage of bilateral chronic subdural hematoma
Shigeta Fujitani, MD1, Osamu Ishikawa, MD, PhD2, Keisuke Miura, MD1, Yasuhiro Takeda, MD1, Haruo Goto, MD1, and Keiichiro Maeda, MD, PhD1 1Department of Neurosurgery, Aizu Chuo Hospital, Aizuwakamatsu, Fukushima; and 2Department of Neurosurgery, Showa General Hospital, Kodaira, Tokyo, Japan
Impact of Glasgow Coma Scale score and pupil parameters on mortality rate and outcome in pediatric and adult severe traumatic brain injury: a retrospective, multicenter cohort study
Pedram Emami, MD1,, Patrick Czorlich, MD1, Friederike S. Fritzsche, MD1, Manfred Westphal, MD1, Johannes M. Rueger, MD2, Rolf Lefering, PhD3, and Michael Hoffmann, MD2Departments of 1Neurosurgery and 2Trauma, Hand, and Reconstructive Surgery, University Medical Center Hamburg-Eppendorf, Hamburg; and 3Institute for Research in Operative Medicine, Witten/Herdecke University, Cologne, Germany
Helmet efficacy against concussion and traumatic brain injury: a review
Je Yeong Sone1, Douglas Kondziolka, MD, MSc1, Jason H. Huang, MD2, and Uzma Samadani, MD, PhD3 1Department of Neurosurgery, New York University School of Medicine, New York, New York; 2Department of Neurosurgery, Baylor Scott & White Central Division, Temple, Texas; and 3Department of Neurosurgery, Hennepin County Medical Center, University of Minnesota, Minneapolis, Minnesota
Treatment of traumatic brain injury in rats with N-acetyl-seryl-aspartyl-lysyl-proline
Yanlu Zhang, MD1, Zheng Gang Zhang, MD, PhD2, Michael Chopp, PhD2,3, Yuling Meng, PhD1, Li Zhang, MD2, Asim Mahmood, MD1, and Ye Xiong, MD, PhD1Departments of 1Neurosurgery and 2Neurology, Henry Ford Hospital, Detroit; and 3Department of Physics, Oakland University, Rochester, Michigan
Traumatic hemorrhagic brain injury: impact of location and resorption on cognitive outcome
Ryan M. Martin, MD1,2, Matthew J. Wright, PhD3, Evan S. Lutkenhoff, PhD4, Benjamin M. Ellingson, PhD, MS5, John D. Van Horn, PhD6, Meral Tubi, BA1, Jeffry R. Alger, PhD2, David L. McArthur, PhD, MPH1, and Paul M. Vespa, MD1,2Departments of 1Neurosurgery, 2Neurology, 3Pyschiatry & Biobehavioral Sciences, 4Psychology, and 5Radiological Sciences, University of California, Los Angeles; and 6Department of Neurology, University of Southern California, Los Angeles, California
Medicare expenditures for elderly patients undergoing surgical clipping or endovascular intervention for subarachnoid hemorrhage
Kimon Bekelis, MD1,2, Daniel J. Gottlieb, MS2, Yin Su, MS2, Giuseppe Lanzino, MD3, Michael T. Lawton, MD4, and Todd A. MacKenzie, PhD2,5,6 1Section of Neurosurgery; 6Department of Medicine, Dartmouth-Hitchcock Medical Center; 2The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon; 5Department of Biomedical Data Science, Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; 3Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota; and 4Department of Neurosurgery, University of California San Francisco Medical Center, San Francisco, California
Comparison of clipping and coiling in elderly patients with unruptured cerebral aneurysms
Kimon Bekelis, MD1, Daniel J. Gottlieb, MS2, Yin Su, PhD2, A. James O’Malley, PhD2,3, Nicos Labropoulos, PhD4, Philip Goodney, MD, MS5,6, Michael T. Lawton, MD7, and Todd A. MacKenzie, PhD2,3,8,9Sections of 1Neurosurgery and 5Vascular Surgery; Departments of 8Medicine and 9Community and Family Medicine, Dartmouth-Hitchcock Medical Center; 2The Dartmouth Institute for Health Policy and Clinical Practice, Lebanon; 3Department of Biomedical Data Science, 6Geisel School of Medicine at Dartmouth, Hanover, New Hampshire; 4Department of Radiology, Stony Brook University Medical Center, Stony Brook, New York; and 7Department of Neurosurgery, University of California, San Francisco Medical Center, San Francisco, California
A long-term study of durability and risk factors for aneurysm recurrence after microsurgical clip ligation
Mason A. Brown, BS1, Jonathan Parish, MD1, Cristian F. Guandique, BA1, Troy D. Payner, MD1, Terry Horner, MD1, Thomas Leipzig, MD1, Karishma V. Rupani, MBBCh1, Richard Kim, MD1, Bradley N. Bohnstedt, MD2, and Aaron A. Cohen-Gadol, MD, MSc1 1Goodman Campbell Brain and Spine, and Department of Neurosurgery, Indiana University, Indianapolis, Indiana; and 2Department of Neurosurgery, Oklahoma University Health Sciences Center, Oklahoma City, Oklahoma
Educational and interactive informed consent process for treatment of unruptured intracranial aneurysms
Jaechan Park, MD, PhD1,2, Wonsoo Son, MD1,2, Ki-Su Park, MD1,2, Dong-Hun Kang, MD1,2, Joomi Lee, PhD3, Chang Wan Oh, MD, PhD4, O-Ki Kwon, MD, PhD4, Taesun Kim, MD, PhD5, and Chang-Hyun Kim, MD6 1Department of Neurosurgery, 2Research Center for Neurosurgical Robotic Systems, and 3Cell & Matrix Research Institute, Kyungpook National University, Daegu; 4Department of Neurosurgery, Seoul National University College of Medicine, Seoul; 5Department of Neurosurgery, Chonnam National University Medical School, Gwangju; and 6Department of Neurosurgery, Keimyung University School of Medicine, Daegu, Republic of Korea
Use of a surgical rehearsal platform and improvement in aneurysm clipping measures: results of a prospective, randomized trial
A. Jessey Chugh, BS1, Jonathan R. Pace, MD2, Justin Singer, MD2, Curtis Tatsuoka, PhD3, Alan Hoffer, MD2, Warren R. Selman, MD2, and Nicholas C. Bambakidis, MD2 1Case Western Reserve University School of Medicine; and Departments of 2Neurological Surgery and 3Neurology, University Hospitals Case Medical Center, Cleveland, Ohio
Seizure outcomes after stereotactic radiosurgery for the treatment of cerebral arteriovenous malformations
Benjamin J. Ditty, MD, Nidal B. Omar, MD, Paul M. Foreman, MD, Joseph H. Miller, MD, Kimberly P. Kicielinski, MD, Winfield S. Fisher III, MD, and Mark R. Harrigan, MDDepartment of Neurosurgery, University of Alabama at Birmingham, Alabama
Comparative analysis of arteriovenous malformation grading scales in predicting outcomes after stereotactic radiosurgery
Bruce E. Pollock, MD1,2, Curtis B. Storlie, PhD3, Michael J. Link, MD1,4, Scott L. Stafford, MD2, Yolanda I. Garces, MD2, and Robert L. Foote, MD2Departments of 1Neurological Surgery, 2Radiation Oncology, 3Biomedical Statistics and Informatics, and 4Otorhinolaryngology, Mayo Clinic College of Medicine, Rochester, Minnesota
Stereotactic radiosurgery for Spetzler-Martin Grade III arteriovenous malformations: an international multicenter study
Dale Ding, MD1, Robert M. Starke, MD, MSc1, Hideyuki Kano, MD, PhD2, John Y. K. Lee, MD, MSCE3, David Mathieu, MD4, John Pierce, MS3, Paul P. Huang, MD5, Caleb Feliciano, MD6, Rafael Rodriguez-Mercado, MD6, Luis Almodovar, MD6, Inga S. Grills, MD7, Danilo Silva, MD8, Mahmoud Abbassy, MD8, Symeon Missios, MD8, Douglas Kondziolka, MD5, Gene H. Barnett, MD8, L. Dade Lunsford, MD2, and Jason P. Sheehan, MD, PhD1 1Department of Neurological Surgery, University of Virginia Health System, Charlottesville, Virginia; 2Department of Neurological Surgery, University of Pittsburgh, and 3Department of Neurosurgery, University of Pennsylvania, Philadelphia, Pennsylvania; 4Division of Neurosurgery, University of Sherbrooke, Centre de recherché du CHUS, Sherbrooke, Quebec, Canada; 5Department of Neurosurgery, NYU Langone Medical Center, New York, New York; 6Section of Neurological Surgery, University of Puerto Rico, San Juan, Puerto Rico; 7Beaumont Health System, Royal Oak, Michigan; and 8Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio
Endoscopic endonasal control of the paraclival internal carotid artery by Fogarty balloon catheter inflation: an anatomical study
Andrea Ruggeri, MD1, Joaquim Enseñat, PhD2, Alberto Prats-Galino, PhD3, Antonio Lopez-Rueda, MD4, Joan Berenguer, PhD4, Martina Cappelletti, MD1, Matteo De Notaris, PhD5, and Elena d’Avella, MD3,6 1Department of Neuroscience, Neurosurgery, University of Rome “Sapienza,” Rome, Italy; 2Department of Neurosurgery, Hospital Clinic, Faculty of Medicine, Universitat de Barcelona, Spain; 3Laboratory of Surgical NeuroAnatomy (LSNA), Human Anatomy and Embryology Unit, Faculty of Medicine, Universitat de Barcelona, Spain; 4Department of Radiology, Hospital Clinic, Faculty of Medicine, Universitat de Barcelona, Spain; 5Neurosurgical Department, “G. Rummo” Hospital of Benevento, Benevento, Italy; and 6Department of Neuroscience, Neurosurgery, University of Padua, Italy
Endoscopic endonasal surgery for nonadenomatous, nonmeningeal pathology involving the cavernous sinus
Aikaterini Patrona, MD1, Kunal S. Patel, MD2, Evan D. Bander, BA2, Alpesh Mehta, MD4, Apostolos John Tsiouris, MD4, Vijay K. Anand, MD5, and Theodore H. Schwartz, MD2,3,4 1Department of Neurosurgery, Medizinische Hochschule Brandenburg, Ruppiner Kliniken, Neuruppin, Germany; and Departments of 2Neurosurgery, 3Neuroscience, 4Radiology, and 5Otolaryngology, Weill Cornell Medical College, NewYork-Presbyterian Hospital, New York, New York
Primary versus revision transsphenoidal resection for nonfunctioning pituitary macroadenomas: matched cohort study
Colin J. Przybylowski, MD1, Robert F. Dallapiazza, MD, PhD1, Brian J. Williams, MD1, I. Jonathan Pomeraniec, BS1, Zhiyuan Xu, MD1, Spencer C. Payne, MD2, Edward R. Laws, MD3, and John A. Jane Jr., MD1Departments of 1Neurosurgery and 2Otolaryngology-Head and Neck Surgery, University of Virginia Health System, Charlottesville, Virginia; and 3Department of Neurosurgery, Brigham and Women’s Hospital, Harvard Medical School, Boston, Massachusetts
Antibiotic prophylaxis for subdural and subgaleal drains
Ariane Lewis, MD1,2, Rajeev Sen, BA3, Travis C. Hill, PhD2,3, Herbert James, BS3, Jessica Lin, MD1, Harpaul Bhamra, MD1, Nina Martirosyan, BS, PharmD4, and Donato Pacione, MD2Departments of 1Neurology and 2Neurosurgery; 3NYU School of Medicine; and 4Pharmacy, NYU Langone Medical Center, New York, New York
Functional anatomy of the accessory nerve studied through intraoperative electrophysiological mapping
Andrei Brînzeu, MD, MSc1,2, and Marc Sindou, MD, DSc1,3 1Neurosurgical Department, Hospital Pierre Wertheimer, University of Lyon; 3University Hospital of Saint-Etienne, France; and 2University of Medicine and Pharmacy “Victor Babes,” Timişoara, Romania
A systematic review of outcomes of contralateral C-7 transfer for the treatment of traumatic brachial plexus injury: an international comparison
Alexandra L. Mathews, BS1, Guang Yang, MD2, Kate Wan-Chu Chang, MA, MS3, and Kevin C. Chung, MD1 1Section of Plastic Surgery, Department of Surgery, The University of Michigan Medical School; 3Section of Plastic Surgery, Department of Surgery, The University of Michigan Health System, Ann Arbor, Michigan; and 2Department of Hand Surgery, China-Japan Union Hospital of Jilin University, Changchun, Jilin, China
A new pattern of lipomatosis of nerve: case report
Nikhil K. Prasad, MBChB1, Mark A. Mahan, MD3, Benjamin M. Howe, MD2, Kimberly K. Amrami, MD2, and Robert J. Spinner, MD1Departments of 1Neurologic Surgery and 2Radiology, Mayo Clinic, Rochester, Minnesota; and 3Department of Neurosurgery, Clinical Neurosciences Center, University of Utah, Salt Lake City, Utah
Struthers’ ligament and traumatic median nerve injury: case illustration
Paule Lessard Bonaventure, MD, and Hélène T. Khuong, MDDepartment of Neurological Sciences, Division of Neurosurgery, CHU de Québec–Université Laval, Québec, Canada
Contralateral supraorbital keyhole approach to medial optic nerve lesions: an anatomoclinical study
Harminder Singh, MD1,, Walid I. Essayed, MD2, Ajit Jada, MD2, Nelson Moussazadeh, MD2,3, Sivashanmugam Dhandapani, MD4, Sarang Rote, MCh2, and Theodore H. Schwartz, MD2 1Department of Neurosurgery, Stanford University School of Medicine, Stanford, California; Department of 2Neurosurgery, Weill Cornell Medical College, NewYork-Presbyterian; 3Division of Neurological Surgery, Memorial Sloan Kettering Cancer Center, New York, New York; and 4Postgraduate Institute of Medical Education and Research, Chandigarh, India
The white matter tracts of the cerebrum in ventricular surgery and hydrocephalus
Abuzer Güngör, MD1, Serhat Baydin, MD1, Erik H. Middlebrooks, MD2,,3, Necmettin Tanriover, MD4, Cihan Isler, MD4, and Albert L. Rhoton Jr., MD1Departments of 1Neurosurgery and 2Radiology, and the 3K. Scott and E. R. Andrew Advanced Neuroimaging Lab, College of Medicine, University of Florida, Gainesville, Florida; and 4Department of Neurosurgery, Cerrahpasa Medical Faculty, Istanbul University, Istanbul, Turkey
The angular course of the median nerve in the distal forearm and its anatomical importance in preventing nerve injury in a modern era of carpal tunnel release
Russell Payne, MD1, Zeinab Nasralah, MS2, Emily Sieg, MD1, Elias B. Rizk, MD, MSc1, Michael Glantz, MD1, and Kimberly Harbaugh, MD1Departments of 1Neurosurgery and 2Ophthalmology, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania
A novel miniature robotic guidance device for stereotactic neurosurgical interventions: preliminary experience with the iSYS1 robot
Georgi Minchev, MD1, Gernot Kronreif, PhD2, Mauricio Martínez-Moreno, MD1, Christian Dorfer, MD1, Alexander Micko, MD1, Aygül Mert, MD1, Barbara Kiesel, MD1, Georg Widhalm, MD, PhD1, Engelbert Knosp, MD1, and Stefan Wolfsberger, MD1 1Department of Neurosurgery, Medical University of Vienna, Vienna; and 2Austrian Center of Medical Innovation and Technology, Wiener Neustadt, Austria
Novel technique of a multifunctional electrosurgical system for minimally invasive surgery
David Mittelstein, BS1, Jiahan Deng, MS2, Rachel Kohan, BS2, Mojdeh Sadeghi, MS2, Jean-Michel Maarek, PhD2, and Gabriel Zada, MD, MS1 1Department of Neurosurgery, Keck School of Medicine, and 2Department of Biomedical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California
Avoiding pullout complications in external ventricular drains: technical note
Carlos Velásquez, MD1, Mónica Rivero-Garvía, MD, PhD2, Maria Jose Mayorga-Buiza, MD, PhD3, María de los Ángeles Cañizares-Méndez, MD4, Manuel E. Jiménez-Mejías, MD, PhD5, and Javier Márquez-Rivas, MD, PhD2 1Department of Neurological Surgery and Spine Unit, Hospital Universitario Marqués de Valdecilla and Fundación Instituto de Investigación Marqués de Valdecilla (IDIVAL), Santander; 2Department of Neurosurgery, 3Department of Pediatric Anesthesia, and 5Infectious Disease Unit, Hospitales Universitarios Virgen del Rocio, Seville; and 4Department of Neurosurgery, Complejo Hospitalario de Toledo, Spain
Language pathway tracking: comparing nTMS-based DTI fiber tracking with a cubic ROIs-based protocol
Chiara Negwer, MD1,2, Nico Sollmann, MD1,2, Sebastian Ille, MD1,2, Theresa Hauck1,2, Stefanie Maurer1,2, Jan S. Kirschke, MD3, Florian Ringel, MD1, Bernhard Meyer, MD1, and Sandro M. Krieg, MD, MBA1,2 1Department of Neurosurgery, 2TUM-Neuroimaging Center, and 3Section of Neuroradiology, Department of Radiology, Klinikum rechts der Isar, Technical University of Munich, Germany
Letter to the Editor: Endoscopic transsphenoidal pituitary surgery
Chih-Chang Chang, MD1,2, Yu-Shu Yen, MD1,2, Tsung-Hsi Tu, MD1,2,3, Li-Yu Fay, MD1,2, Wen-Cheng Huang, MD, PhD1,2, and Jau-Ching Wu, MD, PhD1,2 1Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; 2School of Medicine, National Yang-Ming University, Taipei, Taiwan; and 3Taiwan International Graduate Program in Molecular Medicine, National Yang-Ming University and Academia Sinica, Taipei, Taiwan
Letter to the Editor: Role of mutational status of GNAQ and GNA11 in the diagnosis of melanocytic tumors
Yislenz Narváez-Martínez, MD, MPH, Marc Sagristà-Garcia, MD, and Maria Teresa Fernandez-Figueras, MD, PhDUniversitary Hospital of Girona Dr. Josep Trueta, Girona, Catalonia, Spain; Sant Jaume of Calella Hospital, Calella, Catalonia, Spain; and Universitary Hospital Germans Trias i Pujol, Badalona, Catalonia, Spain
Pages 1024-1026
Response
Klaus G. Griewank, MD, Christian Koelsche, MD, Frederik Wenz, MD, Frank A. Giordano, MD, andChristoffer Gebhardt, MD
Ambuj Kumar, MS, Amandeep Kumar, MCh, Pankaj Kumar Singh, MCh, Shashwat Mishra, MCh, Kanwaljeet Garg, MCh, and Bhawani S. Sharma, MChAll India Institute of Medical Sciences, New Delhi, India
