Pediatric Epilepsy Surgery Preoperative Assessment and Surgical Treatment

Pediatric Epilepsy Surgery Preoperative Assessment and Surgical Treatment

by Oguz Cataltepe (Author), George Jallo (Author)

List Price: $209.99


The definitive guide to surgical management of epilepsy in pediatric patients

This fully revised and updated second edition of Pediatric Epilepsy Surgery, edited by internationally renowned pediatric neurosurgeons and epilepsy surgery experts Oğuz Çataltepe and George Jallo, fills a void in the literature, encompassing the full spectrum of topics related to the surgical treatment of intractable epilepsy and seizures in children. The prodigiously illustrated book and its accompanying videos feature contributions from distinguished specialists in several different countries across a wide range of disciplines.

From epidemiology, genetics, pathology, preoperative electrophysiological assessment and neuroimaging to state-of-the-art surgical approaches, this remarkable resource covers the full depth and breadth of surgical management of pediatric epilepsy. Topics include awake anesthesia, intracranial stimulation and mapping techniques, temporal and extratemporal epilepsy surgery techniques, insular, multilobar and hemispheric surgery approaches, and diverse disconnection, neuromodulation, and ablative procedures. Insights are provided on postoperative issues including seizure control, neuropsychological and psychosocial outcomes, surgical failure and re-operation, and much more.

Key Features

A review of topographic anatomy of the cerebral cortex and white matter with numerous illustrations provides enhanced understanding of eloquent anatomy. Discussion of cutting-edge techniques such as stereo-electroencephalography, multi-modality imaging and tractography, endoscopic and laser ablation approaches in hypothalamic hamartomas, peri-insular quadrantotomy, and various hemispherotomy approaches. Overview of common cortical stimulation and mapping techniques including magnetic and electrical stimulation modalities, functional MRI, and the WADA test. 13 videos demonstrate seizure semiology, stimulation, awake surgery, hemispherotomy, amygdalohippocampectomy, and endoscopic corpus callosotomy. This state-of-the-art resource is a must-have for epilepsy surgeons and epileptologists. It will also greatly benefit neurosurgeons, neurologists, clinical neuropsychologists, electrophysiologists, neuroradiologists, residents, fellows, and medical students involved in the assessment and surgical management of epilepsy in pediatric patients.

This book includes complimentary access to a digital copy on

Update: Canadian Preoperative Prediction Rule for Hydrocephalus

The “Canadian Preoperative Prediction Rule for Hydrocephalus” in children with posterior fossa tumor in childrens which is proposed by Jay Riva-Cambrin is a working system for predicting and decision making.

The system depends on seven different criteria which are assigned scores with a total possible value of 10 and predicts the probability of the need for postoperative hydrocephalus treatment.
A modification of this system was offered, and the “presence of papilledema” was replaced with the presence of “transependymal edema” which can be assessed with computerized tomography (CT) or magnetic resonance imaging.

Riva-Cambrin et al. evaluated a derivation cohort of 343 consecutive children with posterior fossa tumors who underwent treatment between 1989 and 2003. Multivariate methods were used on these data to generate the Canadian Preoperative Prediction Rule for Hydrocephalus. The rule’s estimated risk of postresection hydrocephalus was compared with risk observed in 111 independent patients in the validation cohort.
Variables identified as significant in predicting postresection hydrocephalus were age < 2 years (score of 3), papilledema (score of 1), moderate to severe hydrocephalus (score of 2), cerebral metastases (score of 3), and specific estimated tumor pathologies (score of 1). Patients with scores > or = 5 were deemed as high risk. Predicted probabilities for the high- and low-risk groups were 0.73 and 0.25, respectively, from the derivation cohort, and 0.59 and 0.14 after prevalence adjustment compared with the observed values of 0.42 and 0.17 in the validation cohort.
A patient’s score on the Preoperative Prediction Rule for Hydrocephalus will allow improved patient counseling and surgical planning by identifying patients at high risk of developing postresection hydrocephalus. These patients might selectively be exposed to the risks of preresection CSF diversion to improve outcome 1).
The mCPPRH utilizes readily obtainable and reliable preoperative variables that together stratify children with posterior fossa tumors into high- and low-risk categories for the development of postresection hydrocephalus. This new predictive model will aid patient counseling and tailor the intensity of postoperative clinical and radiographic monitoring for hydrocephalus, as well as provide evidence-based guidance for the use of prophylactic CSF diversion 2).
Low-risk patients can be monitored conservatively with or without an intraoperative external ventricular drainage, while high-risk patients require the use of an intraoperative extraventricular drain, higher postoperative hydrocephalus surveillance, and even consideration for a preoperative endoscopic third ventriculostomy 3).

1) Riva-Cambrin J, Detsky AS, Lamberti-Pasculli M, Sargent MA, Armstrong D, Moineddin R, Cochrane DD, Drake JM. Predicting postresection hydrocephalus in pediatric patients with posterior fossa tumors. J Neurosurg Pediatr. 2009 May;3(5):378-85. doi: 10.3171/2009.1.PEDS08298. PubMed PMID: 19409016.
2) Foreman P, McClugage S 3rd, Naftel R, Griessenauer CJ, Ditty BJ, Agee BS, Riva-Cambrin J, Wellons J 3rd. Validation and modification of a predictive model of postresection hydrocephalus in pediatric patients with posterior fossa tumors. J Neurosurg Pediatr. 2013 Sep;12(3):220-6. doi: 10.3171/2013.5.PEDS1371. Epub 2013 Jun 28. PubMed PMID: 23808727.
3) Lin CT, Riva-Cambrin JK. Management of posterior fossa tumors and hydrocephalus in children: a review. Childs Nerv Syst. 2015 Oct;31(10):1781-9. doi: 10.1007/s00381-015-2781-8. Epub 2015 Sep 9. PubMed PMID: 26351230.
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